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Volume 1, Number 4—October 1995

Dispatch

An Outbreak of Hemoytic Uremic Syndrome Associated with Antibiotic Treatment of Hospital Inpatients for Dysentery

Sami Al-Qarawi*, Robert E. Fontaine†, and Mohammed-Saeed Al-Qahtani*
Author affiliations: *Saudi Arabian Field Epidemiology Training Program, Ministry of Health, Saudi Arabia; †Epidemiology Program Office, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.

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Table 1

Characteristics on hospital admission of dysentery patients whose illness did or did not develop into hemolytic uremic syndrome (HUS) during hospitalization, Najran, Saudi Arabia, March through May 1993

Characteristic Developed HUS (10) Did not develop HUS (32) p valuea
Age (yr mean) 4.4 4.8 0.71
Male sex 7 (70%) 23 (72%) 1.0
Percentile weight for ageb(median) 15.4 16.3 0.57
Below fifth percentile 6 (60%) 12 (38%) 0.29
Days with dysentery (median) 3 3 0.70
Range 2-8 1-14
Stools on first hospital day (median) 12.5 9.0 0.23
Range 2-26 2-43
Temperature (mean) 38.2ºC 38.0ºC 0.64
Range 36.8ºC-39.4ºC 36.5ºC-39.4ºC
Hematocrit (mean) 38.9% 38.8% 0.94
Below 35.5% 4 (40%) 7 (23%) 0.43
Thrombocytes/mm3 555,000 501,000 0.62
Below 150,00000 0 0
Leucocytes/mm3(mean) 11,440 12,300 0.62
Above 12,000 7 (70%) 22 (69%) 1.0
Above 18,000 1 (10%) 4 (13%) 1.0
Serum sodium, mmol/L (mean) 130 134 0.02
Below 130 mmol/L 4 (40%) 7 (22%) 0.41
Serum potassium, mmol/L (mean) 3.4 3.4 0.86
Below 3.5 mmol/L 5 (50%) 16 (50%) 1.0
Serum creatinine, mmol/L (mean) 72 62 0.62
Above 62 mmol/L 5 (50%) 13 (41%) 1.0
BUN, mmol/L (mean) 4.1 3.2 0.06
Above 6.0 mmol/L 2 (20%) 2 (6%) 0.24

aDifferences in means by Student's t-test, in medians by the Kruskal-Wallis test, and in proportions by Fisher's exact test (two-tailed).
bNational Center for Health Statistics.

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