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Volume 10, Number 11—November 2004

Research

Evaluating Human Papillomavirus Vaccination Programs

Al V. Taira*, Christopher P. Neukermans†, and Gillian D. Sanders†‡Comments to Author 
Author affiliations: *Stanford School of Medicine, Stanford, California, USA; †Stanford University, Stanford, California, USA; ‡Duke University, Durham, North Carolina, USA

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Figure 2

A) Vaccine penetration scenario. Relationship between percentage of the population receiving the vaccine and the number of lifetime cervical cancer cases. The solid line represents a female-only vaccination strategy. The dashed line represents a strategy of vaccinating both sexes. The arrow indicates the base-case scenario of a female-only strategy with 70% penetration. B) Vaccine penetration scenario. Relationship between percentage of the population receiving the vaccine and program cost-effec

Figure 2. . A) Vaccine penetration scenario. Relationship between percentage of the population receiving the vaccine and the number of lifetime cervical cancer cases. The solid line represents a female-only vaccination strategy. The dashed line represents a strategy of vaccinating both sexes. The arrow indicates the base-case scenario of a female-only strategy with 70% penetration. B) Vaccine penetration scenario. Relationship between percentage of the population receiving the vaccine and program cost-effectiveness. The solid line represents the cost-effectiveness ($/quality-adjusted life-year [QALY]) of a female-only vaccination program compared to current practice. The dashed line represents the incremental cost-effectiveness of including male participants in a vaccine program compared to a female-only strategy. The arrow indicates the base-case scenario of a female-only program with 70% penetration. C) Vaccine efficacy scenario. Relationship between vaccine efficacy and the number of cohort lifetime cervical cancer cases. The solid line represents a female-only vaccination strategy. The dashed line represents a strategy of vaccinating both sexes. The arrow indicates the base-case scenario of a female-only strategy assuming 90% vaccine efficacy. D) Vaccine efficacy scenario. Relationship between vaccine efficacy and program cost-effectiveness. The solid line represents the cost-effectiveness ($/quality-adjusted life-year [QALY]) of a female-only vaccination program compared to current practice. The dashed line represents the incremental cost-effectiveness of including male participants in a vaccine program compared to a female-only strategy. The arrow indicates the base-case scenario of a female-only program at 90% vaccine efficacy.

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