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Volume 10, Number 3—March 2004

Research

Correlating Epidemiologic Trends with the Genotypes Causing Meningococcal Disease, Maryland

M. Catherine McEllistrem*Comments to Author , John A. Kolano*, Margaret A. Pass†, Dominique A. Caugant‡, Aaron B. Mendelsohn§, Antonio Guilherme Fonseca Pacheco§, Jafar Razeq¶, Lee H. Harrison*†, and the Maryland Emerging Infections Program
Author affiliations: *University of Pittsburgh Graduate School of Public Health and School of Medicine, Pittsburgh, Pennsylvania, USA; †Johns Hopkins University Bloomberg School of Hygiene and Public Health, Baltimore, Maryland, USA; ‡World Health Organization Collaborating Centre for Reference and Research on Meningococci, Norwegian Institute of Public Health, Oslo, Norway; §University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania, USA; ¶Maryland Department of Health and Mental Hygiene, Baltimore, Maryland, USA

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Table 3

Pairwise similarities (% similarity) of serogroup C strains, by age group and time period

Period Age group (y) No. isolates 25% 50% (median) 75% Mean SD p valuea
1992–1999
<14
32
63.6
78.3
87.0
75.4
14.9
<0.01
15–24
28
83.3
87.5
91.7
87.6
7.4
>25
14
64.0
72.7
81.8
74.2
12.1
1992–1997
<14
26
60.9
76.2
84.6
73.1
15.3
<0.01
15–24
20
81.8
88.0
90.9
86.2
7.2
>25
10
61.5
72.7
83.3
73.2
13.7
1998–1999 <14
6
82.6
87.0
95.7
88.9
6.9
<0.01
15–24
8
98.9
100
100
97.0
5.4
>25 4 70.7 72.7 78.2 76.1 8.1

aKruskal-Wallis rank sum test for the comparison of those 15–24 years of age versus each of the two other age groups.

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