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Volume 10, Number 3—March 2004

Synopsis

Reemerging Leptospirosis, California

Elissa Meites*, Michele T. Jay†, Stanley Deresinski†‡, Wun-Ju Shieh§, Sherif R. Zaki§, Lucy Tompkins*, and D. Scott Smith*¶Comments to Author 
Author affiliations: *Stanford University School of Medicine, Stanford, California, USA; †California Department of Health Services, Sacramento, California, USA; ‡Santa Clara Valley Medical Center, San Jose, California, USA; §Centers for Disease Control and Prevention, Atlanta, Georgia, USA; ¶Kaiser Permanente Medical Group, Redwood City, California, USA

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Table 2

Acute- and convalescent-phase serologic and microscopy diagnosis of leptospirosis by MAT,a IgM-ELISA, IHA, and IHC assay in California case reportsb

Case Case 1 Case 2 Case 3 Case 4 Case 5
Days post exposure
9
11
15
32
21
36
23
44
Acute
conv
MAT
ND
ND
Neg
1:3200
Neg
1:800
1:800
1:200
Neg
ND
ELISA
ND
ND
Neg
Pos
Pos
ND
Pos
ND
Pos
ND
IHA
1:50
1:800
ND
ND
ND
ND
ND
ND
ND
1:200
IHC assay NA NA NA Pos Pos

aMAT, microagglutination test. Highest MAT titer reported to any leptospira serogroup.
bIgM-ELISA, immunoglobulin M–Enzyme-Linked ImmunoSorbent Assay; IHA, indirect hemagluttination assay; IHC, immunohistochemical; NA: not available; ND: not done.

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