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Volume 10, Number 4—April 2004

Research

Babesia divergens–like Infection, Washington State

Barbara L. Herwaldt*, Guy de Bruyn†, Norman J. Pieniazek*, Mary Homer‡, Kathryn H. Lofy*§, Susan B. Slemenda*, Thomas R. Fritsche†, David H. Persing‡, and Ajit P. Limaye†Comments to Author 
Author affiliations: *Centers for Disease Control and Prevention, Atlanta, Georgia, USA; †University of Washington, Seattle, Washington, USA; ‡Corixa Corporation, Seattle, Washington, USA; §Washington State Department of Health, Olympia, Washington, USA

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Table 2

Results of testing of serial specimens obtained from a patient in Washington State infected with a Babesia divergens-like parasitea

Dateb Examination of smears of whole blood for Babesia parasites IFA titers to B. divergens antigensc PCR
July 31, 2002
Positive (parasitemia level, 28.2%)
1:64
Positive
September 10
NPF
1:1,024
Positive
October 25
NPF
1:1,024
Positive
November 8
NPF
1:256
Negative
December 12
NPF
1:256
Negative
April 14, 2003 NPF 1:256 Negative

aIFA, indirect fluorescent antibody; PCR, polymerase chain reaction; NPF, no parasites found.
bSee Table 1 for values of other laboratory testing performed on or near dates listed here. Patient received antibabesial therapy from July 31 (before July 31 specimen obtained) through August 26, 2002. Hamsters injected with patient’s blood obtained July 31 and August 1 did not become demonstrably parasitemic, nor did jirds injected with blood from September 10.
cAll of the serum specimens were tested at the Centers for Disease Control and Prevention on same day.

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