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Volume 10, Number 4—April 2004

Synopsis

Pediatric Influenza Prevention and Control

Nicola Principi*Comments to Author  and Susanna Esposito*
Author affiliations: *Institute of Pediatrics, University of Milan, Milan, Italy

Main Article

Table 3

Effectiveness of influenza vaccine among household contacts of children receiving influenza vaccine and unvaccinated controlsa

Event Household contacts of vaccinated children (n = 728)b Household contacts of unvaccinated controls (n = 370)b Vaccine effectiveness, %c p value
No. of respiratory tract infections
3.03 ± 1.68
4.27 ± 1.68
30
0.0005
No. of medical visits because of respiratory illness
2.18 ± 1.37
3.16 ± 1.77
32
0.002
Loss of maternal work, days
3.22 ± 1.86
4.78 ± 2.34
33
0.001
Loss of paternal work, days
0.56 ± 0.46
0.98 ± 2.24
43
0.001
Help at home to care for ill children, days 0.57 ± 0.37 3.22 ± 2.24 83 <0.0001

aModified from S. Esposito et al. (39).
bMean values ± standard deviation.
cVaccine effectiveness: 1 minus attack rate (defined as rate of illness divided by the total population) among household contacts of vaccinated children divided by attack rate among household contacts of controls.

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