Volume 10, Number 4—April 2004
Pneumocystis jiroveci Dihydropteroate Synthase Genotypes in Immunocompetent Infants and Immunosuppressed Adults, Amiens, France
|Risk factor for Pneumocystis infection
|No. of patients
|Median age (range)
||4.3 mo (1.9–11.8)
||35 y (29–67)
|Sex ratio, M/F
|Period of specimen retrieval
||November 1999–April 2001
||June 1996–November 2001
|Kind of specimens
|Method of P. jirovecii detection
||Both microscopyd and PCR assay
|Form of Pneumocystis infection||Colonizatione||Pneumocystis pneumonia|
aYoung age renders it compatible with primary Pneumocystis infection.
bHIV infection (n = 9), renal transplant (n = 2), and long-term corticosteroid treatment (n = 2).
cPCR, polymerase chain reaction assay, at the mitochondrial large sub-unit rRNA gene.
dMethanol-Giemsa stain and immunofluorescence assay (Bio-Rad, Marnes la Coquette, France).
eClinical improvement observed despite the absence of treatment for the fungus.
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