Volume 10, Number 5—May 2004
Research
Acute Tick-borne Rickettsiosis Caused by Rickettsia heilongjiangensis in the Russian Far East
Oleg Y. Mediannikov*†‡
, Yuri Sidelnikov†, Leonid Ivanov§, Eugenia Mokretsova†, Pierre-Edouard Fournier‡, Irina Tarasevich*, and Didier Raoult‡
, Yuri Sidelnikov†, Leonid Ivanov§, Eugenia Mokretsova†, Pierre-Edouard Fournier‡, Irina Tarasevich*, and Didier Raoult‡Table 3
Serologic data of 11 patients with Rickettsia infectiona
| Patient no. | Disease onset date | Antimicrobial treatmentc | PCR |
|||||||
|---|---|---|---|---|---|---|---|---|---|---|
| gltA gene | ompA and ompB genes | Sera | Collection date | R. heilongjiangensis | R. hulinensis | R. sibirica | R. conorii | |||
| 1 | 6/18 | 6/23 | + | NI | 1 | 6/24 | 0 | 0 | 0 | 0 |
| 2 | 6/28 | 1/1024 | 1/512 | 1/512 | 1/1,024 | |||||
| 2 | 6/20 | 6/23 | + | + | 1 | 6/24 | 0 | 0 | 0 | 0 |
| 2 | 7/9 | 0 | 0 | 0 | 0 | |||||
| 3 | 6/21 | 6/24 | + | NI | 1 | 6/5 | 0 | 0 | 0 | 0 |
| 2 | 7/12 | 0 | 0 | 0 | 0 | |||||
| 4 | 6/22 | 6/26 | + | NI | 1 | 6/26 | 1/64 | 1/64 | 1/64 | 1/64 |
| 2 | 7/1 | 1/2,048 | 1/512 | 1/512 | 1/2048 | |||||
| 5 | 6/22 | 6/28 | + | NI | 1 | 6/28 | 0 | 0 | 0 | 0 |
| 2 | 7/16 | 1/128 | 1/128 | 1/128 | 1/128 | |||||
| 6 | 6/29 | 7/2 | + | + | 1 | 7/3 | 0 | 0 | 0 | 0 |
| 2 | 7/8 | 1/128 | 1/64 | 1/64 | 1/128 | |||||
| 7 | 6/30 | 7/4 | + | NI | 1 | 7/5 | 0 | 0 | 0 | 0 |
| 2 | 7/16 | 1/256 | 1/128 | 1/256 | 1/256 | |||||
| 8 | 7/1 | 7/8 | + | NI | 1 | 7/8 | 0 | 0 | 0 | 0 |
| 2 | 7/26 | 0 | 0 | 0 | 0 | |||||
| 9 | 7/6 | 7/12 | + | NI | 1 | 7/15 | 1/1,024 | 1/1,024 | 1/1,024 | 1/1,024 |
| 2 | 7/31 | 1/1,024 | 1/1,024 | 1/1,024 | 1/1,024 | |||||
| 10 | 7/23 | 7/28 | + | + | 1 | 7/29 | 0 | 0 | 0 | 0 |
| 2 | 8/13 | 1/1,024 | 1/1,024 | 1/256 | 1/256 | |||||
| 11 | 7/25 | 8/1 | + | NI | 1 | 8/2 | 1/256 | 1/256 | 1/128 | 1/128 |
| 2 | 8/15 | 1/256 | 1/256 | 1/128 | 1/128 | |||||
aPCR, polymerase chain reaction; Ig, immunoglobulin; NI, not investigated.
bIgG tests used.
cDate of beginning of antimicrobial drug therapy.
