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Volume 10, Number 5—May 2004

Research

Enzyme-Linked Immunosorbent Assay and Serologic Responses to Pneumocystis jiroveci

Kieran R. Daly*Comments to Author , Judy Koch*, Linda Levin*, and Peter D. Walzer*
Author affiliations: *University of Cincinnati College of Medicine, Cincinnati, Ohio, USA; ‡Veterans Affairs Medical Center, Cincinnati, Ohio, USA

Main Article

Table 3

Adjusted odds ratios (95% CI) measuring the associations between Western blot reactivity and participant status (blood donor versus PCP-positive, PCP-negative, HIV) among 189 study participantsa,b

ELISA Midpoint Blood donor: PCP+ (95% CI) Blood donor: PCP– (95% CI) Blood donor: HIV (95% CI)
1
2.7
3.2 (1.6 to 6.7)
2.2 (1.4 to 3.5)
2.7 (1.7 to 4.3)
2
16
5.9 (2.5 to 14.3)
3.2 (2.0 to 5.3)
4.3 (2.6 to 7.4)
3 35 10.0 (2.9 to 33.3) 9.1 (4.4 to 20.0) 9.4 (4.6 to 19.3)

aCI, confidence interval; ELISA, enzyme-linked immunosorbent assay; PCP, Pneumocystis pneumonia.
bOdds ratios measuring the association between Western blot reactivity and participant status were calculated at the midpoints of ELISA measurements over all antigens. Based on 95% confidence intervals, blood donors had significantly increased odds of Western blot reactivity compared to each patient group (p < 0.05) for each ELISA.

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