Emerging Infectious Disease ISSN: 1080-6059

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Virulence Factors for Hemolytic Uremic Syndrome, Denmark¹

Steen Ethelberg*

, Katharina E. P. Olsen*, Flemming Scheutz*†, Charlotte Jensen*, Peter Schiellerup*, Jørgen Engberg*, Andreas Munk Petersen*, Bente Olesen*, Peter Gerner-Smidt*, and Kåre Mølbak*

Author affiliations: *Statens Serum Institut, Copenhagen, Denmark; †The World Health Organization International Escherichia Centre, Copenhagen, Denmark

Main Article

Table 4

Risk factors for bloody diarrhea among 343 STEC patients, Denmark, 1997–2003^a

			Univariate analysis		Multivariate analysis
Determinant	No. of patients	No. (%) with BD	OR	95% CI	OR	95% CI
eae
Negative	111	17 (15.3)	1		1
Positive	232	108 (46.6)	4.8	2.7 to 8.6	6.0	2.7 to 13.3
stx₂
Negative	159	41 (25.8)	1		1
Positive	184	84 (45.7)	2.4	1.5 to 3.8	2.5	1.2 to 5.1
O157
No	262	69 (26.3)	1		1
Yes	81	56 (69.1)	6.3	3.6 to 10.8	2.7	1.2 to 5.7
O103
No	298	104 (34.9)	1		1
Yes	45	21 (46.7)	1.6	0.9 to 3.1	2.8	1.2 to 6.3
ehxA
No	79	15 (19.0)	1
Yes	264	110 (41.7)	3.0	1.7 to 5.6	NS
Age^b	-	-	-	-	1.3	1.2 to 1.5

^aSTEC, Shiga toxin–producing Escherichia coli; BD, bloody diarrhea; OR, odds ratio; CI, confidence intervals; NS, not statistically significant.
^bCalculated for an increase in age of 10 years.

Main Article

¹Presented in part at the VTEC2003, 5th International Symposium on “Shiga Toxin (Verocytotoxin) Producing Escherichia coli Infections,” Edinburgh, Scotland, June 2003 (abstract O-6).

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