Skip directly to search Skip directly to A to Z list Skip directly to page options Skip directly to site content

Volume 10, Number 5—May 2004

Research

Laboratory Diagnosis of SARS

Paul K.S. Chan*Comments to Author , Wing-Kin To†, King-Cheung Ng*, Rebecca K. Y. Lam*, Tak-Keung Ng†, Rickjason C. W. Chan*Comments to Author , Alan Wu*, Wai-Cho Yu†, Nelson Lee*, David S. C. Hui*, Sik-To Lai†, Ellis K. L. Hon*, Chi-Kong Li*, Joseph J. Y. Sung*, and John S. Tam*
Author affiliations: *The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China; †Princess Margaret Hospital, Kowloon, Hong Kong SAR, China

Main Article

Table 2

Diagnostic yield of specimen types to detect SARS-CoV according to time of collectiona


No. positive specimens/no. tested for SARS-CoV (%)
RT-PCR Virus isolation
Specimen type
1 week
2 weeks
3–4 weeks

1 week
2 weeks
3–4 weeks
Respiratory







Tracheal aspirate
1/2 (50.0)
1/1 (100)
4/4 (100)

2/3 (66.7)
1/1 (100)
0/3
Pooled throat and nasal swabs
6/17 (35.3)
2/3 (66.7)
2/5 (40.0)

4/18 (22.2)
0/3
0/1
Nasal swab
9/27 (33.3)
5/14 (35.7)
1/17 (5.9)

3/29 (10.3)
2/18 (11.1)
0/19
Nasopharyngeal aspirate
39/138 (28.3)
15/44 (34.1)
6/10 (60.0)

23/171 (13.5)
6/54 (11.1)
0/9
Throat swab
5/19 (26.3)
5/14 (35.7)
3/10 (30.0)

2/23 (8.7)
0/15
1/15 (6.7)
Throat washing
4/40 (10.0)
13/58 (22.4)
1/48 (2.1)

0/36
1/62 (1.6)
0/51
Nonrespiratory







Rectal swab
5/11 (45.5)
2/10 (20.0)
3/7 (42.9)

0/14
0/12
0/35
Stool
9/21 (42.9)
17/25 (68.0)
34/80 (42.5)

2/24 (8.3)
0/28
0/141
Urine 2/75 (2.7) 5/82 (6.1) 6/54 (11.1) 0/110 0/86 2/76 (2.6)

aSARS-CoV, severe acute respiratory syndrome–associated coronavirus; RT-PCR, reverse transcription–polymerase chain reaction.

Main Article

TOP