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Volume 10, Number 6—June 2004

Research

Sporadic Cryptosporidiosis, North Cumbria, England, 1996–2000

Stella Goh*, Mark Reacher†Comments to Author , David P. Casemore‡, Neville Q. Verlander†, Rachel Chalmers§, Margaret Knowles¶, Joy Williams*, Keith Osborn#, and Sarah Richards**
Author affiliations: *Carlisle and District Primary Care Trust, Rosehill, Carlisle, United Kingdom; †Communicable Disease Surveillance Centre, London, United Kingdom; ‡University of Wales, Aberystwyth, Ceredigion, Wales, United Kingdom; §Singleton Hospital, Swansea, Wales, United Kingdom; ¶Cumberland Infirmary, Carlisle, United Kingdom; #United Utilities, Great Sankey, Warrington, United Kingdom; **West Cumberland Hospital, Whitehaven, United Kingdom

Main Article

Table 1

Recruitment and reasons for exclusion from study, United Kingdom (UK)

Exclusion criteria No. (%) excluded
Case-patients (n = 207)
Refusal to participate 1 (0.5)
Could not complete adequate interview 1 (0.5)
Did not respond to letters or phone calls 2 (1.0)
Not meeting the study case definition
  No history of diarrhea 1 (0.5)
  Mixed enteric infection 1 (0.5)
Secondary case 36 (17.4)
Travel outside the UK in 14 days before onset 8 (3.9)
Travel in UK outside study area for >7 nights in the 14 days before onset 1 (0.5)
Visitor to study area 1 (0.5)
Residence outside study area 1 (0.5)
Case-patient or household member previously interviewed as case-patient or control 2(1.0)
  Total potential cases excluded
55 (26.6)
  Total cases enrolled 152 (73.4)
Controls (n = 778)
Refusal to participate in interview 23 (3.0)
Unavailable at requested interview times 125 (16.1)
Said interview times were not convenient 35 (4.5)
  Subtotal: refused, unavailable for interview 183 (23.5)
Address not found 3 (0.4)
History of diarrhea 46 (5.9)
Travel outside UK in the 14 days before interview 8 (1.0)
Travel in UK outside study area for >7 nights in the 14 days before interview 2 (0.3)
Not resident in study area in the 14 days before interview 3 (0.4)
Moved from study area 27 (3.5)
Resident outside study area 2 (0.3)
Control or household member already interviewed as a case-patient or control 7 (0.9)
  Subtotal: did not meet study control definition 95 (12.2)
Interview cancelled by study team because three controls already enrolled for associated case 19 (2.4)
Interview cancelled by study team as potential control found to be in wrong age group 9 (1.2)
Reason for exclusion not recorded 3 (0.4)
  Subtotal: not enrolled for administrative reasons or reason not recorded 31 (4.0)
  Total potential controls excluded
312 (40.1)
  Total controls enrolled 466 (59.9)

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