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Volume 10, Number 6—June 2004

Dispatch

Predominant Tuberculosis Spoligotypes, Delhi, India

Urvashi Balbir Singh*, Naga Suresh*, N.Vijaya Bhanu*, Jyoti Arora*, Hema Pant*, Sanjeev Sinha*, Ram Charan Aggarwal*, Sushma Singh*, Jitendra Nath Pande*, Christophe Sola†, Nalin Rastogi†, and Pradeep Seth*
Author affiliations: *All India Institute of Medical Sciences, New Delhi, India; †Institut Pasteur de Guadeloupe, Pointe-à-Pitre, Guadeloupe

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Table 1

Clinical and epidemiologic characteristics of patients harboring clustered versus nonclustered strainsa

Parameters No. (%) of patients in
Clustered group Nonclustered group OR for clustering (95% CI) p value
Age, y
15–45 63 (81) 15 (19) 4.52 (1.6 to 12.96) 0.001
>46 13 (48) 14 (52)
Sex
Male 53 (72) 21 (28) 0.88 (0.30 to 2.49) NS
Female 23 (74) 8 (26)
HIV status
Seropositive 2 (100) 0 (0) UD
Seronegative 74 (72) 29 (28)
Previous history of TB
No previous therapy 52 (80) 13 (20) 2.53 (0.89 to 7.22) 0.05
Previously treated 19 (61) 12 (39)
Drug resistance
Drug resistanceb 22 (71) 6 (29) 1.56 (0.51 to 4.97) NS
Susceptible to all drugs 54 (70) 23 (30)
Radiologic findings
Extensive cavitary 12 (76) 5 (24) 1.6 (0.33 to 11.22) NS
Limited cavitary 6 (60) 4 (40)
Sputum smear positive
1–10 AFB/10–100 fields 30 (73) 11 (27) 0.96 (0.34 to 2.70) NS
>1 AFB per field 37 (74) 13 (26)

aOR, odds ratio; CI, confidence interval; TB, tuberculosis; NS, not statistically significant; UD, undefined; AFB, acid-fast bacilli.
bResistance to one or more drugs.

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