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Volume 10, Number 7—July 2004

Research

Recombinant Viruses and Early Global HIV-1 Epidemic

Marcia L. Kalish*Comments to Author , Kenneth E. Robbins*, Danuta Pieniazek*, Amanda Schaefer*, Nzila Nzilambi†, Thomas C. Quinn†‡, Michael E. St. Louis*†, Ae S. Youngpairoj*, Jonathan Phillips*, Harold W. Jaffe*, and Thomas M. Folks*
Author affiliations: *Centers for Disease Control and Prevention, Atlanta, Georgia, USA; †Project SIDA, Kinshasa, Zaire; ‡National Institutes of Health, Bethesda, Maryland, USA

Main Article

Table 1

Comparison of intrasubtype/CRF genetic distances and subtype distributiona

Subtype/CRF Kinshasa: mid-1980s DRC: 1997

n
Nucleotide distance (%)
% frequency of subtype
n
Nucleotide distance (%)
% frequency of subtype
A
22
15.1
44
84
20.8b
46
C
3
13.1
6
18
18.0b
10
D
10
12.1
20
23
18.7b
13
CRF01-AE
3
9.6
6
4
17.9b
2
G
5
15.6
10
15
20.1b
8
F1
3
10.0
6
7
14.8b
4
H
2
18.7
4
16
23.5
9
J
1

2
7
21.2
4
K 1 2 7 20.4 4

aCRF, circulating recombinant forms; DRC, Democratic Republic of Congo
bSignificant difference (distances significance test = t test, frequency of subtypes significance test = Fisher exact test).

Main Article

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