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Volume 10, Number 8—August 2004

Research

Predicting Antigenic Variants of Influenza A/H3N2 Viruses

Min-Shi Lee*Comments to Author  and Jack Si-En Chen*
Author affiliations: *MedImmune Vaccines, Mountain View, California, USA

Main Article

Table 2

Antigenic distance (upper right) and number of amino acid changes in the HA1 (lower left) in 55 pairwise comparisons among 11 influenza H3N2 viruses

Virus IDa H3N2 virus
A B C D E F G H I J K
A. HK/71

27.7
19.6
39.2
55.4
39.2
48.0
39.2
110.9
67.9
110.9
B. ENG/72
15

4.0
26.1
16.0
64.0
156.8
4.0
64.0
78.4
181.0
C. PC/73
16
7

8.0
16.0
32.0
27.7
22.6
37.0
55.4
90.5
D. MC/75
21
12
12

9.2
32.0
45.3
32.0
90.5
55.4
90.5
E. VIC/75
30
19
19
15

11.3
27.7
1.9
5.7
78.4
128.0
F. TOK/75
20
17
18
16
20

78.4
45.3
26.1
39.2
90.5
G. ENG/75
27
18
17
8
17
22

32.0
4.6
6.9
19.6
H. AC/76
31
20
18
16
6
21
19

9.2
78.4
73.9
I. VIC/76
32
21
19
17
2
22
19
4

27.7
32.0
J. BAN/1/79
36
25
23
21
24
33
17
26
26

9.2
K. BAN/2/79 36 24 24 22 26 33 20 28 28 3

aID, identification.

Main Article

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