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Volume 10, Number 9—September 2004

Research

Silent Nucleotide Polymorphisms and a Phylogeny for Mycobacterium tuberculosis

Lucy Baker*, Tim Brown*, Martin Maiden†, and Francis Drobniewski*Comments to Author 
Author affiliations: *Heal Protection Agency, London, UK; †University of Oxford, Oxford, UK

Main Article

Table 4

Relationship between Mycobacterium tuberculosis lineage and continent of birth of patienta

Lineage n Europe
Africa
Indian subcontinent
Southeast Asia
Eur Not Eur OR p value Afr Not Afr OR p value ISC Not ISC OR p value SEA Not SEA OR p value
I 17 5 12 0.86 0.997 1 16 0.17 0.079 1 16 0.12 0.034 10 7 28.8 < 0.00001
II 118 59 59 6.4 < 0.00001 33 85 1.34 0.473 19 99 0.2 < 0.00001 4 114 0.21 0.006
III 50 3 47 0.1 0.00001 9 41 0.58 0.245 37 13 11.31 < 0.00001 0 50 0.0 0.009
IV 40 5 35 0.25 0.005 15 25 2.04 0.08 15 25 1.36 0.514 5 35 1.66 0.166
Total 225 72 153 58 167 72 153 19 206

aOR, odds ratio; Eur, Europe; Afr, Africa; ISC, Indian subcontinent; SEA, southeast Asia.

Main Article

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