Emerging Infectious Disease ISSN: 1080-6059

Genetic Divergence and Dispersal of Yellow Fever Virus, Brazil

Pedro F.C. Vasconcelos*

, Juliet E. Bryant†, Amelia P.A. Travassos da Rosa†, Robert B. Tesh†, Sueli G. Rodrigues*, and Alan D.T. Barrett†

Author affiliations: *World Health Organization Collaborating Center for Arbovirus Reference and Research, Instituto Evandro Chagas, Belém, Brazil; †University of Texas Medical Branch, Galveston, Texas, USA

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Figure 3

Sequence alignment of the fusion peptide of the envelope (E) gene of selected yellow fever virus (YFV) strains (E98–E110). The Asibi prototype strain indicates the conserved sequence present in the majority of YFV strains and other mosquitoborne flaviviruses. A salt bridge between residues Asp E98 and Lys E110 generates the "CD loop" of residues E100–E108 (21).

Figure 3. . Sequence alignment of the fusion peptide of the envelope (E) gene of selected yellow fever virus (YFV) strains (E98–E110). The Asibi prototype strain indicates the conserved sequence present in the majority of YFV strains and other mosquitoborne flaviviruses. A salt bridge between residues Asp E98 and Lys E110 generates the "CD loop" of residues E100–E108 (21).

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