TY - JOUR AU - Zhang, Mingdong AU - Sun, Xiu-Di AU - Mark, Steven D. AU - Chen, Wen AU - Wong, Lara AU - Dawsey, Sanford M. AU - Qiao, You-Lin AU - Fraumeni, Joseph F. AU - Taylor, Philip R. AU - O’Brien, Thomas R. T1 - Hepatitis C Virus Infection, Linxian, China T2 - Emerging Infectious Disease journal PY - 2005 VL - 11 IS - 1 SP - 17 SN - 1080-6059 AB - Bloodborne viruses may have spread in rural China during the past 25 years, but population-based prevalence estimates are lacking. We examined the frequency of hepatitis C virus (HCV) and HIV type 1 (HIV-1) among residents of Linxian, a rural community in Henan Province. In 2000, blood was collected from participants (>55 years of age) who had enrolled in a population-based nutritional intervention trial in 1985. We randomly selected 500 participants for HCV testing and 200 participants for HIV-1 testing. For HCV, 48 (9.6%) of 500 participants were positive by enzyme immunoassay and recombinant immunoblot assay (95% confidence interval [CI], 7.0%–12.2%), and prevalence was lowest in the most geographically isolated participants. Among the HCV-infected participants, 42 had a specimen available from1985, of which 16 (38.1%) were positive for HCV. For HIV-1, 0/200 participants were positive. We conclude that HCV is now a common infection among older adults in Linxian, China. KW - AIDS KW - China KW - epidemiology KW - hepatitis B virus (HBV) KW - hepatitis C virus (HCV) KW - human immunodeficiency virus type 1 (HIV-1) KW - liver cancer KW - prevalence KW - research DO - 10.3201/eid1101.031005 UR - https://wwwnc.cdc.gov/eid/article/11/1/03-1005_article ER - End of Reference