TY - JOUR AU - Buck, Jessica AU - Como-Sabetti, Kathryn AU - Harriman, Kathleen AU - Danila, Richard AU - Boxrud, David AU - Glennen, Anita AU - Lynfield, Ruth T1 - Community-associated Methicillin-resistant Staphylococcus aureus, Minnesota, 2000–2003 T2 - Emerging Infectious Disease journal PY - 2005 VL - 11 IS - 10 SP - 1532 SN - 1080-6059 AB - We compared characteristics of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) skin and soft tissue infections (SSTIs) and CA-MRSA invasive disease identified in Minnesota from 2000 through 2003. A total of 586 patients with SSTIs and 65 patients with invasive disease were identified. Patients with invasive disease were more likely to be smokers (p = 0.03), and report a history of immunosuppressive therapy (p = 0.03), emphysema (p = 0.011), or injection drug use (p = 0.020) than were SSTI patients. Invasive disease isolates were less likely to be susceptible to ciprofloxacin (p = 0.002) and clindamycin (p = 0.001) and more likely to have healthcare-associated pulsed-field gel electrophoresis subtypes than SSTI isolates (p<0.001). Patients with invasive disease may have had healthcare exposures that put them at risk of acquiring healthcare-associated MRSA and which were not exclusion criteria in the CA-MRSA case definition. Continued surveillance of MRSA is needed to better characterize CA-MRSA infections. KW - Staphylococcal infections KW - methicillin resistance KW - community-acquired infections KW - research KW - Minnesota KW - United States DO - 10.3201/eid1110.050141 UR - https://wwwnc.cdc.gov/eid/article/11/10/05-0141_article ER - End of Reference