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Volume 11, Number 12—December 2005

Research

Viral Load Distribution in SARS Outbreak

Chung-Ming Chu*, Vincent C.C. Cheng†, Ivan F.N. Hung†, Kin-Sang Chan*, Bone S.F. Tang†, Thomas H.F. Tsang‡, Kwok-Hung Chan†, and Kwok-Yung Yuen†Comments to Author 
Author affiliations: *United Christian Hospital, Hong Kong Special Administrative Region, People's Republic of China; †University of Hong Kong, Hong Kong Special Administrative Region, People's Republic of China; ‡Department of Health, Hong Kong Special Administrative Region, People's Republic of China

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Table

Demographic factors on admission of patients living in E block and non-E block of Amoy Gardens, Hong Kong*

Factor E block patients (n = 53) Non-E block patients (n = 26) p value
Age, y, mean (SD) 40.6 (11.9) 37.1 (10.6) 0.21†
Male:female ratio 25:28 13:13 0.81‡
Duration of symptoms to admission (days), mean (SD) 2.4 (1.2) 2.5 (1.2) 0.72†
Coexisting conditions including chronic hepatitis B, no. (%) 11 (19.6) 8 (30.8) 0.33‡
Chronic hepatitis B infection, no. (%) 5 (9.4) 5 (19.2) 0.22‡
Abnormal chest radiograph results, no. (%) 38 (71.7) 21 (80.8) 0.38‡
Multilobar involvement on initial chest radiograph, no. (%) 13 (24.5) 5 (19.2) 0.60‡
Day of collection of nasopharyngeal specimens after onset of symptoms, mean (SD) 3.2 (1.2) 3.3 (1.8) 0.74†
Quantitative RT-PCR result of nasopharyngeal specimens (log10 copies/mL), median (IQR) 5.09 (3.50–6.59) 0 (0–3.57) 0.008§
Hemoglobin (g/dL), mean (SD) 13.3 (1.7) 13.8 (1.4) 0.24†
Neutrophil count (× 109/L), mean (SD) 5.2 (2.0) 5.3 (2.0) 0.77†
Lymphocyte count (× 109/L), mean (SD) 0.92 (0.6) 0.86 (0.4) 0.65†
Sodium (mmol/L), mean (SD) 138 (3) 138 (3) 0.91†
Potassium (mmol/L), mean (SD) 3.9 (3.6) 3.9 (3.0) 0.31†
Urea (mmol/L), mean (SD) 4.4 (1.4) 4.1 (1.0) 0.34†
Creatinine (μmol/L), mean (SD) 88 (16) 85 (12) 0.35†
Alanine aminotransferase (IU/L), mean (SD) 41 (49) 31 (19) 0.31†
Albumin (g/L), mean (SD) 40 (3) 40 (3) 0.85†
Creatinine kinase (IU/L), mean (SD) 197 (222) 190 (186) 0.89†
Lactate dehydrogenase (IU/L), mean (SD) 437 (190) 398 (107) 0.47†

*SD, standard deviation; IQR, interquartile ratio; RT-PCR, reverse transcription–polymerase chain reaction.

†By Student t test.

‡By chi-square test.

§By Mann-Whitney U test.

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