Central African Hunters Exposed to Simian Immunodeficiency Virus
Marcia L. Kalish* , Nathan D. Wolfe†, Clement B. Ndongmo*, Janet McNicholl*, Kenneth E. Robbins*, Michael Aidoo*, Peter N. Fonjungo*‡, George Alemnji‡, Clement Zeh*, Cyrille F. Djoko§, Eitel Mpoudi-Ngole‡, Donald S. Burke†, and Thomas M. Folks*
Author affiliations: *Centers for Disease Control and Prevention, Atlanta, Georgia, USA; †Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA; ‡Project IRECAM (Investigation of Retroviruses in Cameroon), Yaoundé, Cameroon; §Johns Hopkins Cameroon Program, Yaoundé, Cameroon
Figure 2. Interferon-γ enzyme-linked immunospot reactivity stimulated with SIVcol peptides from the env and gag regions in peripheral blood lymphocytes (PBLs) from a person seropositive for both the SIVcol V3 and immunodominant region (IDR) peptides and a seronegative person from Africa (both men). To include both assays in a single graph, the number of spots per 106 PBLs for each pool of gag peptides was divided by the number of spots per 106 PBLs in the medium control. This value was expressed as the level of reactivity above background; i.e., the value 2 on the y-axis stands for 2× the number of spots in the negative (medium) control.
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