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Volume 11, Number 12—December 2005

Research

Postepizootic Persistence of Venezuelan Equine Encephalitis Virus, Venezuela

Juan-Carlos Navarro*, Gladys Medina†, Clovis Vasquez‡, Lark L. Coffey§, Eryu Wang§, Alexander Suárez*‡, Hernán Biord#, Marlene Salas¶, and Scott C. Weaver§Comments to Author 
Author affiliations: *Universidad Central de Venezuela, Caracas, Venezuela; †Instituto Nacional de Investigaciones Agropecuarias, Maracay, Venezuela; ‡Instituto Nacional de Higiene, Caracas, Venezuela; #Sociedad Venezolana de Ciencias Naturales, Venezuela; ¶Ministerio de Agricultura y Tierras, Barinas, Venezuela; §University of Texas Medical Branch, Galveston, Texas, USA

Main Article

Table 5

Sequence comparisons between the year 2000 VEEV virus equine isolates and those from the 1995 epidemic*

Virus strain† State of isolation Horse sample Date of collection Passage history Comparisons to 1995 strain 6119
Comparisons to 1995 strain 3908
nt differences‡ aa differences§ nt differences¶ aa differences#
254934 Barinas Brain Apr 10, 2000 sm-1 C1248T A1443G
G6325A nsP4/V208I T4975C
G9165A E2/E199K C5292T
T10913C T5475C
C11237T G6325A nsP4/V208I
A6498T
G9159A E2/E199K
C11237T
255010 Barinas Serum Feb 20, 2000 sm-2 C1248T A1443G
T10913C T4975C
C11237T C5292T
T5475C
A6498T
G9159A E2/E199K
C11237T
255005* Barinas Serum Feb 20, 2000 sm-3 0 0
255057* Carabobo Brain April, 2000 sm-1, V-1 0 0

*VEEV, Venezuelan equine encephalitis virus; nt, nucleotide; aa, amino acid.

†Only partial PE2 envelope glycoprotein precursor gene sequences determined (817 nucleotides).

‡Strain 6119 residue is indicated first, followed by genome position and year 2000 strain residue.

§Strain 6119 residue is indicated first, followed by protein and amino acid position and year 2000 strain residue.

¶Strain 3908 residue is indicated first, followed by genome position and year 2000 strain residue.

#Strain 3908 residue is indicated first, followed by protein and amino acid position and year 2000 strain residue.

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