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Volume 11, Number 2—February 2005
Research

Rickettsial Infection in Animals and Brazilian Spotted Fever Endemicity

Luis A. Sangioni*†, Maurício C. Horta*, Manoella C.B. Vianna*, Solange M. Gennari*, Rodrigo M. Soares*, Márcio A.M. Galvão‡, Teresinha T.S. Schumaker*, Fernando Ferreira*, Odilon Vidotto§, and Marcelo B. Labruna*Comments to Author 
Author affiliations: *University of São Paulo, São Paulo, São Paulo, Brazil; †Centro Integrado de Ensino Superior – Campus Universitário, Campo Mourão, Paraná, Brazil; ‡Federal University of Ouro Preto, Ouro Preto, Minas Gerais, Brazil; §Londrina State University, Londrina, Paraná, Brazil

Main Article

Table

Results of indirect immunofluorescence assay for antibodies to Rickettsia rickettsii in humans and domestic animals from 3 BSF-endemic areas (farms 1–3)* and 3 BSF-nonendemic areas (farms 4–6), São Paulo, Brazil†

Source Reactive sera‡/total sera tested (% reactive)
Farm 1 Farm 2 Farm 3 Farm 4 Farm 5 Farm 6
Humans 0/20 (0) 0/21 (0) 0/9 (0) 0/4 (0) 0/2 (0) 0/10 (0)
Horses 9/10 (90) 4/7 (57.1) 4/5 (80) 0/16 (0) 0/10 (0) 0/21 (0)
Dogs 1/4 (25) 4/6 (66.7) 0/6 (0) No dogs 0/4 (0) 0/1 (0)

*Data from Horta et al. (17).
†BSF, Brazilian spotted fever.
‡Sera showing titers ≥64 for R. rickettsii antigen.

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References
  1. Gonçalves  AJR, Lopes  PFA, Melo  JCP, Pereira  AA, Pinto  AMM, Lazera  MS, Rickettsioses. A propósito de quatro casos diagnosticados no Rio de Janeiro de febre amculosa barsileira. Folha Med. 1981;82:12734.
  2. Sexton  DJ, Muniz  M, Corey  GR, Breitschwerdt  EB, Hegarty  BC, Dumler  S, Brazilian spotted fever in Espirito Santo, Brazil: description of a focus of infection in a new endemic region. Am J Trop Med Hyg. 1993;49:2226.PubMedGoogle Scholar
  3. Lemos  ERS, Machado  RD, Coura  JR. Rocky Mountain spotted fever in an endemic area in Minas Gerais, Brazil. Mem Inst Oswaldo Cruz. 1994;89:497501. DOIPubMedGoogle Scholar
  4. Lemos  ER, Alvarenga  FB, Cintra  ML, Ramos  MC, Paddock  CD, Ferebee  TL, Spotted fever in Brazil: a seroepidemiological study and description of clinical cases in an endemic area in the state of Sao Paulo. Am J Trop Med Hyg. 2001;65:32934.PubMedGoogle Scholar
  5. Lemos  ER, Rozental  T, Villela  CL. Brazilian spotted fever: description of a fatal clinical case in the State of Rio de Janeiro. Rev Soc Bras Med Trop. 2002;35:5235. DOIPubMedGoogle Scholar
  6. Galvao  MA, Lamounier  JA, Bonomo  E, Tropia  MS, Rezende  EG, Calic  SB, Rickettsioses emergentes e reemergentes numa região endêmica do estado de Minas Gerais, Brazil. Cad Saude Publica. 2002;18:15937. DOIPubMedGoogle Scholar
  7. Galvao  MA, Calic  SB, Chamone  CB, Mafra  SCL, Cesarino Filho  G, Olano  JP, Spotted fever rickettsiosis in Coronel Fabriciano, Minas Gerais State. Rev Soc Bras Med Trop. 2003;36:47981. DOIPubMedGoogle Scholar
  8. Gomes  LS. Thypho exanthematico de São Paulo. Bras Med. 1933;17:91921.
  9. Moreira  JA, Magalhães  O. Thypho exanthematico em Minas Gerais. Bras Med. 1935;44:46570.
  10. Dias  E, Martins  A, Ribeiro  DJ. Thypho exanthematico no Oeste de Minas Gerais. Bras Med. 1937;51:6515.
  11. Lima  VLC, Figueiredo  AC, Pignatti  MG, Modolo  M. Febre maculosa no município de Pedreira, Estado de São Paulo, Brasil: Relação entre ocorrência de casos e parasitismo humano por ixodídeos. Rev Soc Bras Med Trop. 1995;28:1357.PubMedGoogle Scholar
  12. Guimarães  JH, Tucci  EC, Barros-Battesti  DM. Ectoparasitos de importância veterinária. São Paulo: Editora Plêiade; 2001.
  13. Labruna  MB, Kerber  CE, Ferreira  F, Faccini  JLH, De Waal  DT, Gennari  SM. Risk factors to tick infestations and their occurrence on horses in the State of São Paulo, Brazil. Vet Parasitol. 2001;97:114. DOIPubMedGoogle Scholar
  14. Lima  VL, Souza  SS, Souza  CE, Vilela  MF, Papaiordanou  PM, Del Guercio  VM, Situação da febre maculosa na região administrativa de Campinas, São Paulo, Brasil. Cad Saude Publica. 2003;19:3314. DOIPubMedGoogle Scholar
  15. Burgdorfer  W. Ecological and epidemiological considerations of Rocky Mountain spotted fever and scrub typhus. In: Walker DH, editor. Biology of rickettsial diseases. Vol. 1. Boca Raton (FL): CRC Inc.; 1988. p. 33–50.
  16. Burgdorfer  W, Hayes  SF, Mavros  AJ. Nonpathogenic rickettsiae in Dermacentor andersoni: a limiting factor for the distribution of Rickettsia rickettsii. In: Burgdorfer W, Anacker RL, editors. Rickettsiae and rickettsial diseases. New York: Academic Press; 1981. p.585–94.
  17. Horta  MC, Labruna  MB, Sangioni  LA, Vianna  MCB, Gennari  MS, Galvão  MAM, Prevalence of antibodies to spotted fever group rickettsiae in humans and domestic animals in a Brazilian Spotted fever endemic area in the state of São Paulo, Brazil: serological evidence for infection by Rickettsia rickettsii and another spotted fever group rickettsia. Am J Trop Med Hyg. 2004;71:937.PubMedGoogle Scholar
  18. Labruna  MB, Kasai  N, Ferreira  F, Faccini  JLH, Gennari  SM. Seasonal dynamics of ticks (Acari: Ixodidae) on horses in the state of São Paulo, Brazil. Vet Parasitol. 2002;105:6572. DOIPubMedGoogle Scholar
  19. Labruna  MB, Whitworth  T, Horta  MC, Bouyer  DH, McBride  JW, Pinter  A, Rickettsia species infecting Amblyomma cooperi ticks from an endemic area for Brazilian spotted fever in the state of São Paulo, Brazil. J Clin Microbiol. 2004;42:908. DOIPubMedGoogle Scholar
  20. Burgdorfer  W. The hemolymph test. Am J Trop Med Hyg. 1970;19:10104.PubMedGoogle Scholar
  21. Gimémez  DF. Staining rickettsiae in yolk-sac cultures. Stain Technol. 1964;39:13540.PubMedGoogle Scholar
  22. Chomkzynski  P. A reagent for the single-step simultaneous isolation of RNA, DNA and proteins from cell and tissue samples. Biotechniques. 1993;15:5327.PubMedGoogle Scholar
  23. Regnery  RL, Spruill  CL, Plikaytis  BD. Genotypic identification of rickettsiae and estimation of intraspecies sequence divergence for portions of two rickettsial genes. J Bacteriol. 1991;173:157689.PubMedGoogle Scholar
  24. Webb  L, Carl  M, Malloy  DC, Dasch  GA, Azad  AF. Detection of murine typhus infection in fleas by using the polymerase chain reaction. J Clin Microbiol. 1990;28:5304.PubMedGoogle Scholar
  25. Hanson  BA, Wisseman  CL Jr, Waddell  A, Silverman  DJ. Some characteristics of heavy and light bands of Rickettsia prowazekii on Renografin gradients. Infect Immun. 1981;34:596604.PubMedGoogle Scholar
  26. Lemos  ERS, Machado  RD, Coura  JR, Guimarães  MAA, Chagas  N. Epidemiological aspects of the Brazilian spotted fever: serological survey of dogs and horses in an endemic area in the state of São Paulo, Brazil. Rev Inst Med Trop Sao Paulo. 1996;38:42730. DOIPubMedGoogle Scholar
  27. Galvão  MAM. Febre maculosa em Minas Gerais: um estudo sobre a distribuição da doença no Estado e seu comportamento em área de foco peri-urbano [Doctoral thesis]. Belo Horizonte: Faculdade de Medicina da UFMG; 1996. p. 114.
  28. Vallejo-Freire  A. Spotted fever in Mexico. Memórias doInstituto Butantan.1946;19:159–80.
  29. Patino-Camargo  L. Nuevas observaciones sobre un tercer foco de fiebre petequial (maculosa) en el hemisferio americano. Bol Oficina Sanit Panam. 1941;20:11124.
  30. Bustamante  ME, Varela  G. Estudios de fiebre manchada en Mexico. Hallazgo del Amblyomma cajennense naturalmente infectado, en Veracruz. Rev Inst Salubr Enferm Trop. 1946;7:758.
  31. Rodaniche  EC. Natural infection of the tick Amblyomma cajennense with Rickettsia rickettsii in Panama. Am J Trop Med Hyg. 1953;2:6969.PubMedGoogle Scholar
  32. Goddard  J. Experimental infection of lone star ticks, Amblyomma americanum (L.), with Rickettsia parkeri and exposure of guinea pigs to the agent. J Med Entomol. 2003;40:6869. DOIPubMedGoogle Scholar
  33. Lackman  D, Parker  R, Geloff  R. Serological characteristics of a pathogenic rickettsia occuring in Amblyomma maculatum. Public Health Rep. 1949;64:13429. DOIPubMedGoogle Scholar
  34. Venzal  JM, Portillo  A, Estrada-Peña  A, Castro  O, Cabrera  PA, Oteo  JA. Rickettsia parkeri in Amblyomma triste from Uruguay. Emerg Infect Dis. 2004;10:14935.PubMedGoogle Scholar
  35. Paddock  CD, Sumner  JW, Comer  JA, Zaki  SR, Goldsmith  CS, Goddard  J, Rickettsia parkeri: a newly recognized cause of spotted fever rickettsiosis in the United States. Clin Infect Dis. 2004;38:1521. DOIPubMedGoogle Scholar

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