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Volume 11, Number 3—March 2005

Research

Methicillin-resistant Staphylococcus aureus in Horses and Horse Personnel, 2000–2002

J.S. Weese*Comments to Author , M. Archambault*, H. Dick‡, P. Hearn§, B.N. Kreiswirth§, B. Said-Salim¶, A. McGeer†, Y. Likhoshvay¶, J.F. Prescott*, D.E. Low†, and B.M.Willey
Author affiliations: *University of Guelph, Guelph, Ontario, Canada; †Mount Sinai Hospital, Toronto, Ontario, Canada; ‡Vita-Tech Laboratories, Markham, Ontario, Canada; §Hearn Veterinary Services, Orangeville, Ontario, Canada; ¶New York University Medical Center, New York, New York, USA

Main Article

Table

In vitro antimicrobial susceptibilities of 101 methicillin-resistant Staphylococcus aureus isolates from humans and horses*

Antimicrobial agent MIC in μg/mL
% of isolates
50% 90% Range Intermediate Resistant
Tetracycline >16 >16 <4–>16 0 96
Doxycycline 8 8 <4–8 78.2 0
Minocycline <4 <4 <4–8 14.8 0
Erythromycin >8 >8 <0.5–>8 0 86.1
Gentamicin >16† >16† <2–>16† 9.9 88.1
Rifampicin >4 >4 <1–>4 10.9 71.2
TMP/SMX 8/152 >8/152 <2/38–8/152 NA 79.2

*MIC, minimum inhibitory concentration; TMP/SMX, trimethoprim-sulfamethoxazole; NA, no intermediate MIC category in NCCLS guidelines.
†All strains were susceptible to gentamicin at a concentration of 500 μg/mL.

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