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Volume 11, Number 3—March 2005

Dispatch

SARS-associated Coronavirus Transmitted from Human to Pig

Weijun Chen*†1, Minghua Yan‡1, Ling Yang*1, Boliang Ding‡, Bo He†, Yingzhen Wang‡, Xiuli Liu‡, Chenhui Liu*, Hui Zhu‡, Bo You†, Shengyong Huang†, Jiangguo Zhang*, Feng Mu*†, Zhao Xiang*§, Xiaoli Feng*, Jie Wen*†, Jianqiu Fang*†, Jun Yu*, Huanming Yang*, and Jian Wang*†Comments to Author 
Author affiliations: *Chinese Academy of Sciences, Beijing, China; †Beijing BGI-GBI Biotech Co., Ltd, Beijing, China; ‡Tianjin Institute of Animal Husbandry and Veterinary Science, Tianjin, China; §BGI Hangzhou Bio-Environment Technology Co., Ltd, Hangzhou, China; 1W. Chen, M. Yan, and L. Yang contributed equally to this article.

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Table 1

Animal surveys for antibodies to SARS-CoV and viral RNA*

Animals Antibodies in serum samples
RT-PCR
Virus isolation
ELISA
WB
Blood
Fecal swab
Blood
Fecal swab
N P N P N P N P N P N P
Pigs 108 2 5 2 14 1 14 1 6 1 6 1
Cattle 60 0 0 0 22 0 0 0 0 0 0 0
Dogs 20 0 0 0 14 0 0 0 0 0 0 0
Cats 11 0 0 0 11 0 0 0 0 0 0 0
Chickens 11 0 0 0 11 0 0 0 0 0 0 0
Ducks 30 0 0 0 20 0 0 0 0 0 0 0

*Numbers in table refer to number of animals tested with the assays. SARS-CoV, severe acute respiratory syndrome–associated coronavirus; RT-PCR, reverse transcriptase–polymerase chain reaction; ELISA, enzyme-linked immunosorbent assay; WB, Western blot; N, negative; P, positive.

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