Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 11, Number 4—April 2005
Research

Experimental Infection of Prairie Dogs with Monkeypox Virus

Shu-Yuan Xiao*, Elena Sbrana*, Douglas M. Watts*, Marina Siirin*, Amelia P.A. Travassos da Rosa*, and Robert B. Tesh*Comments to Author 
Author affiliations: *University of Texas Medical Branch, Galveston, Texas, USA

Main Article

Table 1

Results of virus titration of serial blood and throat swab samples taken from prairie dogs after experimental monkeypox infection

Day after infection Animal no.*
MPX-1
MPX-3
MPX-4
MPX-5
MPX-6
MPX-7
MPX-8
MPX-9
B TS B TS B TS B TS B TS B TS B TS B TS
1 0 NT 0 NT 0 NT 0 NT 0 NT 0 NT 0 NT 0 NT
2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
3 0 0 0 0 0 0 0 0.7 0 0 0 0 0 1.0 0 0
4 0 0 0 0 0 0 0 0.7 0 0 0 2.4 0 0.7 0 1.6
5 0 0 0.7 0.7 1.9 1.9 0 2.2 0 0 0 2.6 0 1.5 0 1.7
6 1.2† 1.4 1.7 1.5 3.9 3.2 0 3.2 0 2.4 0 1.4 0 1.2 0 1.4
7 2.4 3.0 2.3 2.5 5.4 4.2 0 3.6 0 1.9 0 2.7 0 2.0 0 2.0
8 2.5 3.2 3.5 1.7 D D 0 3.6 0 1.6 0 2.7 0 2.3 1.5 3.2
9 4.0 4.3 D D 1.4 4.6 1.6 2.7 1.4 2.6 3.4 3.5 1.2 4.5
10 5.3 5.1 1.0 4.8 3.5 3.0 2.1 3.7 4.4 2.5 3.6 5.0
11 D D 1.4 5.0 D D 1.9 3.9 4.0 4.4 3.8 5.1
12 1.2 5.1 2.3 4.7 4.4 4.7 4.3 5.2
13 2.4 5.1 2.0 3.5 4.0 5.1 D D
14 NT NT D D NT NT
15 4.5 4.4 4.0 5.0
16 NT 4.3 NT 5.0
17 NT 3.2 NT 5.2
18 NT 2.1 NT 5.0
19 NT 2.9 NT 4.8
20 NT 1.7 NT 4.2
21 NT 1.0 NT 4.0
22 NT 0 NT 2.9

*Animals MPX-1, MPX-3, and MPX-4 were infected intraperitoneally; animals MPX-5 to MPX-9 were infected intranasally.
†Indicates titer of monkeypox virus in sample; log10 PFU/mL of sample (blood [B] or throat swab diluent [TS]); 0, <100.7 PFU/mL; NT, not tested; D, animal dead.

Main Article

Page created: May 23, 2011
Page updated: May 23, 2011
Page reviewed: May 23, 2011
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external