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Volume 11, Number 6—June 2005

Letter

Measuring Impact of Antimicrobial Resistance

Mary-Claire Roghmann*Comments to Author , Douglas D. Bradham†, Min Zhan*, Scott K. Fridkin‡, and Trish M. Perl§
Author affiliations: *University of Maryland School of Medicine, Baltimore, Maryland, USA:; †VA Maryland Health Care System, Baltimore, Maryland, USA; ‡Centers for Disease Control and Prevention, Atlanta, Georgia, USA; §Johns Hopkins Medical Institutions, Baltimore, Maryland, USA

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Table

Description of 187 adult patients with central vascular catheter-associated bloodstream infections with Staphylococcus aureus or Enterococcus faecium attributable to the intensive care unit*

Characteristics S. aureus (n = 109) E. faecium (n = 78) p value
Patient demographics
Male (%) 74 56 0.02
Mean age, y (SD) 58 (17) 56 (16) 0.32
Type of ICU <0.01
Cardiac (%) 20 10
Cardiothoracic surgery (%) 6 6
Medical (%) 20 40
Neurologic/neurosurgical (%) 6 0
Surgical (%) 20 37
Trauma (%) 28 6
Severity of illness
Mean APACHE II score at ICU admission (SD) 19 (8) 21 (9) 0.12
Mean APACHE II score within 7 days of BSI (SD) 17 (8) 20 (8) 0.05
Resistant infections (%) 50 69 0.01
In-hospital death rate (%) 34 54 <0.01

*SD, standard deviation; ICU, intensive care unit.

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