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Volume 11, Number 6—June 2005
Research

Emergence and Spread of Streptococcus pneumoniae with erm(B) and mef(A) Resistance

David J. Farrell*Comments to Author , Stephen G. Jenkins†, Steven D. Brown‡, Manish Patel§, Bruce S. Lavin§, and Keith P. Klugman¶#
Author affiliations: *G.R. Micro Ltd, London, United Kingdom; †Mount Sinai School of Medicine, New York, New York, USA; ‡Clinical Microbiology Institute, Wilsonville, Oregon, USA; §sanofi-aventis, Bridgewater, New Jersey, USA; ¶Emory University, Atlanta, Georgia, USA; #University of the Witwatersrand, Johannesburg, South Africa

Main Article

Table 1

Geographic distribution by year of Streptococcus pneumoniae collected from years 1 to 3 of the PROTEKT US study with both erm(B)- and mef(A)-encoded macrolide resistance among genotyped erythromycin-resistant isolates

US region* No. erm(B)+mef(A)–positive/no. erythromycin-resistant (%)
Year 1 Year 2 Year 3 Years 1–3 combined
North-Central 121/667 (18.1) 117/626 (18.7) 176/735 (23.9) 414/2,028 (20.4)
Northeast 88/985 (8.9) 96/771 (12.5) 140/900 (15.6) 324/2,656 (12.2)
Northwest 8/98 (8.2) 18/119 (15.1) 26/125 (20.8) 52/342 (15.2)
South-Central 23/561 (4.1) 36/463 (7.8) 80/667 (12.0) 139/1,691 (8.2)
Southeast 29/427 (6.8) 31/481 (6.4) 49/475 (10.3) 109/1,383 (7.9)
Southwest 35/395 (8.9) 37/333 (11.1) 49/275 (17.8) 121/1,003 (12.1)
Total 304/3,133 (9.7) 335/2,793 (12.0) 520/3,177 (16.4) 1,159/9,103 (12.7)

*North-Central = Illinois, Iowa, Kansas, Minnesota, Missouri, Nebraska, North Dakota, South Dakota, Wisconsin; Northeast = Connecticut, Delaware, Indiana, Maryland, Massachusetts, Michigan, New Jersey, New York, Ohio, Pennsylvania, Rhode Island, Vermont, Washington DC; Northwest = Alaska, Idaho, Montana, Oregon, Washington, Wyoming; South-Central = Alabama, Arkansas, Louisiana, Oklahoma, Tennessee, Texas; Southeast = Florida, Georgia, Kentucky, North Carolina, Puerto Rico, South Carolina, Virginia, West Virginia; Southwest = Arizona, California, Colorado, Nevada, New Mexico, Utah.

Main Article

Page created: April 24, 2012
Page updated: April 24, 2012
Page reviewed: April 24, 2012
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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