Emerging Infectious Disease ISSN: 1080-6059

Human Coronavirus NL63, France

Astrid Vabret*

, Thomas Mourez*, Julia Dina*, Lia van der Hoek†, Stéphanie Gouarin*, Joëlle Petitjean*, Jacques Brouard*, and François Freymuth*

Author affiliations: *University Hospital, Caen, France; †University of Amsterdam, Amsterdam, the Netherlands

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Figure 3

A) Phylogenetic analysis of a 523-bp region of the partial spike gene of 12 human coronavirus (HCoV)-NL63 isolates from France. To construct the trees, the 2 prototype strains NL63-Amsterdam1 and NL-AY518894 were included. HCoV-229E is used as an outgroup. A) Nucleotide sequence alignments created with ClustalX 1.83; bootstrap values ≥70 are indicated. B) Predicted amino acid sequences; bootstrap values ≥50 are indicated.

Figure 3. . A) Phylogenetic analysis of a 523-bp region of the partial spike gene of 12 human coronavirus (HCoV)-NL63 isolates from France. To construct the trees, the 2 prototype strains NL63-Amsterdam1 and NL-AY518894 were included. HCoV-229E is used as an outgroup. A) Nucleotide sequence alignments created with ClustalX 1.83; bootstrap values ≥70 are indicated. B) Predicted amino acid sequences; bootstrap values ≥50 are indicated.

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