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Volume 11, Number 8—August 2005
Dispatch

Evaluating Antibiograms To Monitor Drug Resistance

Mohamed El-Azizi*, Adnan Mushtaq*, Cheryl Drake†, Jerry Lawhorn†, Joan Barenfanger†, Steven Verhulst*, and Nancy Khardori*Comments to Author 
Author affiliations: *Southern Illinois University, Springfield, Illinois, USA; †Memorial Medical Center, Springfield, Illinois, USA

Main Article

Table A2

Comparison of susceptibility results of common gram-positive bacteria to selected antimicrobial agents in 4 regions of central Illinois*

Organism/region (no. isolates tested) % isolates susceptible (no. isolates reported)
AMP AMP/SUL CFZ CFT LEV TMP/SMX CFO OXA PEN ERY CLN TET VAN
Staphylococcus aureus
   West (2,201) 7 (1,987) 51 (1,932) 72 (2,201) 64 (1,803) 97 (2,016) 73 (2,201) 51 (1,803) 70 (2,201) 93 (2,044) 100 (2,201)
   Southwest 982) 12 (615) 84 (774) 81 (882) 50 (553) 95 (982) 47 (777) 42 (874) 54 (974) 91 (982) 100 (982)
   Central (5,313) 14 (3,036) 64 (1,969) 62 (1,376) 62 (4,650) 99 (4,500) 66 (5,344) 48 (4,565) 65 (5,340) 96 (4,598) 100 (5,199)
   South (1,582) 13 (1,582) 50 (854) 48 (1,582) 45 (1,313) 96 (1,582) 45 (219) 36 (1,582) 50 (269) 87 (1,363) 100 (1,007)
   p value <0.0001 <0.0001 <0.0001 <0.0001 <0.0001 <0.0001 <0.0001 <0.0001 NA
Streptococcus pneumoniae
   West (248) 93 (240) 99 (156) 84 (245) 67 (234) 59 (93) 100 (234)
   Southwest (51) 84 (51) 80 (23) 84 (51) 74 (38) 77 (13) 96 (28)
   Central (782) 82 (319) 99 (366) 80 (366) 64 (768) 64 (630) 100 (750)
   South (223) 96 (223) 99 (121) 66 (29) 75 (16) 52 (158) 100 (86)
   p value <0.0001 <0.0001 0.0843 0.4417 0.0256 <0.0001
Coagulase-negative staphylococci
   West (2,066) 6 (1,868) 32 (2,206) 46 (2,066) 100 (2,066)
   Southwest (816) 29 (729) 73 (816) 55 (816) 100 (816)
   Central (3,583) 30 (716) 24 (1,125) 78 (1,473) 100 (3,583)
   South (97) 8 (54) 44 (54) 64 (97) 100 (97)
   p value <0.0001 <0.0001 <0.0001 NA
Enterococcus faecalis
   West (803) 97 (707) 47 (803) 43 (803) 99 (803)
   Southwest (414) 84 (414) 56 (136) 44 (236) 91 (414)
   Central (3,797) 94 (3,152) 40 (2,087) 41 (2,143) 96 (3,763)
   South (873) 93 (873) 32 (454) 40 (579) 96 (873)
   p value <0.0001 <0.0001 0.5635 <0.0001
E. faecium
   West (273) 20 (270) 40 (286) 32 (273)
   Southwest (100) 22 (100) 30 (100 NV
   Central (215) 22 (212) 32 (56) 55 (215)
   South (419) 68 (419) 55 (125) 73 (419)
   p value <0.0001 0.0065 NA

*AMP, ampicillin; AMP/SUL, ampicillin/sulbactam; CFZ, cefazolin; CFT, ceftriaxone; LEV, levofloxacin; TMP/SMX, trimethoprim/sulfamethoxazole; CFO, cefotaxime; OXA, oxacillin; PEN, penicillin; ERY, erythromycin; CLN, clindamycin; TET, tetracycline; VAN, vancomycin; NA, not applicable; NV, not available.

Main Article

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