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Volume 11, Number 8—August 2005

Perspective

Virology, Pathology, and Clinical Manifestations of West Nile Virus Disease

Edward B. Hayes*Comments to Author , James J. Sejvar†, Sherif R. Zaki†, Robert S. Lanciotti*, Amy V. Bode*, and Grant L. Campbell*
Author affiliations: *Centers for Disease Control and Prevention, Fort Collins, Colorado, USA; †Centers for Disease Control and Prevention, Atlanta Georgia, USA

Main Article

Figure

Histopathologic features of West Nile virus (WNV) in human tissues. Panels A and B show inflammation, microglial nodules, and variable necrosis that occur during WNV encephalitis; panel C shows WNV antigen (red) in neurons and neuronal processes using an immunohistochemical stain; panel D is an electron micrograph of WNV in the endoplasmic reticulum of a nerve cell (arrow). Bar = 100 nm.

Figure. . Histopathologic features of West Nile virus (WNV) in human tissues. Panels A and B show inflammation, microglial nodules, and variable necrosis that occur during WNV encephalitis; panel C shows WNV antigen (red) in neurons and neuronal processes using an immunohistochemical stain; panel D is an electron micrograph of WNV in the endoplasmic reticulum of a nerve cell (arrow). Bar = 100 nm.

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