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Volume 12, Number 10—October 2006

Research

Campylobacter jejuni Multilocus Sequence Types in Humans, Northwest England, 2003–2004

Will Sopwith*Comments to Author , Andrew Birtles†, Margaret Matthews†, Andrew Fox†, Steven Gee‡, Michael Painter*, Martyn Regan*, Qutub Syed*, and Eric Bolton†
Author affiliations: *Health Protection Agency (North West), Liverpool, United Kingdom; †Regional Health Protection Agency Laboratory, Manchester, United Kingdom; ‡Cumbria and Lancashire Health Protection Unit, Preston, United Kingdom

Main Article

Table 2

Comparative distributions of the most common MLST clonal complexes by study area, April 2003 to March 2004*

Clonal complex Isolates
Incidence/100,000
Incidence ratio 95% confidence intervals p value
Rural Suburban Rural Suburban
ST–21 36 66 19.91 15.50 1.28 0.83–1.96
ST–45 21 14 11.61 3.29 3.53 1.71–7.51 <0.001
UA 12 22 6.64 5.17 1.28 0.58–2.71
ST–257 9 19 4.98 4.46 1.12 0.44–2.59
ST–443 6 15 3.32 3.52 1.01 0.32–2.80
ST–48 6 13 3.32 3.05 1.09 0.34–3.07
ST–206 8 10 4.42 2.35 1.88 0.65–5.30
ST–353 4 9 2.21 2.11 1.05 0.24–3.75
ST–22 2 5 1.11 1.17 0.94 0.09–5.75
ST–49 2 5 1.11 1.17 0.94 0.09–5.75
C. coli 16 14 8.85 3.29 2.69 1.23–5.95 <0.01
All cases† 181 312 100.08 73.25 1.37 1.13–1.65 <0.001

*Including UA (new sequence types as yet unassigned to a clonal complex), Campylobacter coli isolates, and all cases of campylobacteriosis reported. Annual estimated incidence was calculated for each clonal complex and incidence ratios were calculated for rural incidence/suburban incidence, including confidence intervals. Those data with a statistically significant difference between the study areas are shown in boldface type (level of significance p<0.05). MLST, multilocus sequence typing.
†Refers to the entire dataset for reference, i.e., those shown in this table plus all others.

Main Article

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