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Volume 12, Number 12—December 2006

Research

Distinct Transmission Cycles of Leishmania tropica in 2 Adjacent Foci, Northern Israel

Milena Svobodova*, Jan Votypka*, Jitka Peckova*, Vít Dvorak*, Abedelmajeed Nasereddin†, Gad Baneth†, Julia Sztern†, Vasiliy Kravchenko†, Amnon Orr‡, David Meir§, Lionel F. Schnur†, Petr Volf*, and Alon Warburg†Comments to Author 
Author affiliations: *Charles University, Prague, Czech Republic; †The Hebrew University of Jerusalem, Jerusalem, Israel; ‡Tiberias Veterinary Center, Tiberias, Israel; §Nature and National Parks Protection Authority, Jerusalem, Israel

Main Article

Table 3

Characterization of Leishmania tropica isolates from the Galilee foci, northern Israel*

Focus/ source Monoclonal antibody specificity
Excreted factor serotype
L. major T1 L. major/L. tropica T3 L. tropica T11
Northern
  Phlebotomus arabicus 5+ 5+ ± A4
  Girl with CL† 4+ 5+ A4
  Rock hyrax 5+ 5+ ± A4
Southern
  P. sergenti 4+ 3+ A9B2
  Man with CL† 2+ 4+ A9B2
Reference strains
  L. major 5+ 5+ A1
  L. tropica ± 3+ 3+ A9

*Characterization was performed by using excreted factor serotyping (23) and species-specific monoclonal antibodies (14). CL, cutaneous leishmaniasis. Values indicate relative intensity of fluorescence under UV light. L. tropica isolates from the northern focus were antigenically similar to L. major and distinct from other L. tropica strains.
†Specimens were isolated by skin scraping for diagnostic purposes at the Department of Dermatology at Hadassah Hospital, Jerusalem.

*Characterization was performed by using excreted factor serotyping (23) and species-specific monoclonal antibodies (14). CL, cutaneous leishmaniasis. Values indicate relative intensity of fluorescence under UV light. L. tropica isolates from the northern focus were antigenically similar to L. major and distinct from other L. tropica strains.
†Specimens were isolated by skin scraping for diagnostic purposes at the Department of Dermatology at Hadassah Hospital, Jerusalem.

*Characterization was performed by using excreted factor serotyping (23) and species-specific monoclonal antibodies (14). CL, cutaneous leishmaniasis. Values indicate relative intensity of fluorescence under UV light. L. tropica isolates from the northern focus were antigenically similar to L. major and distinct from other L. tropica strains.
†Specimens were isolated by skin scraping for diagnostic purposes at the Department of Dermatology at Hadassah Hospital, Jerusalem.

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