Wanda Markotter*, Ivan Kuzmin†, Charles E. Rupprecht†, Jenny Randles‡, Claude T. Sabeta§, Alexander I. Wandeler¶, and Louis H. Nel*
Author affiliations: *University of Pretoria, Pretoria, South Africa; †Centers for Disease Control and Prevention, Atlanta, Georgia, USA; ‡Allerton Veterinary Laboratory, Pietermaritzburg, South Africa; §Onderstepoort Veterinary Research Institute, Pretoria, South Africa; ¶Canadian Food Inspection Agency, Nepean, Ontario, Canada
Figure 2. Pathogenicity of genotype 2 (LBVSA2004 [white bars] and Mongoose2004 [black bars]) and genotype 1 (gray bars) lyssaviruses in mice. Results are percentages of dead animals observed for a specific period. Mice were observed for 56 days, but no deaths occurred after 18 days. A) Deaths after intracerebral injection of 103 50% lethal doses (LD50). B) Deaths after intramuscular injections of 105 LD50.
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