Volume 12, Number 12—December 2006
Dispatch
Spongiform Encephalopathy in a Miniature Zebu
Torsten Seuberlich*1
, Catherine Botteron*1, Christian Wenker†, Valeria Café-Marçal*, Anna Oevermann*, Bianca Haase*, Tosso Leeb*, Dagmar Heim‡, and Andreas Zurbriggen*
, Catherine Botteron*1, Christian Wenker†, Valeria Café-Marçal*, Anna Oevermann*, Bianca Haase*, Tosso Leeb*, Dagmar Heim‡, and Andreas Zurbriggen*Table 2
Histopathologic lesions in brain of zebu with spongiform encephalopathy and cow with bovine spongiform encephalopathy, Switzerland, 2004*
| Site | Cow | Zebu |
|---|---|---|
| Brainstem | ||
| Dorsal motor nucleus of vagus nerve | + | ++ |
| Nucleus of spinal tract of trigeminal nerve | ++ | +++ |
| Nucleus of hypoglossal nerve | + | ++ |
| Reticular formation | ++ | ++ |
| Nucleus of solitary tract | ++ | +++ |
| Vestibular nucli | ++ | + to ++ |
| Olivary nuclei | ++ | ++ |
| Cerebellar cortex | – | + |
| Midbrain (substantia grisea centralis) | + to ++ | ++ to +++ |
| Thalamus | ++ | ++ to +++ |
| Hippocampus | n.d. | + |
| Basal nuclei (pallidum) | + | + |
| Cerebral cortex | + | ++
*–, absent; +, mild; ++, moderate; +++ severe; n.d., not done. |
*–, absent; +, mild; ++, moderate; +++ severe; n.d., not done.
1These authors contributed equally to this work.
