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Volume 12, Number 3—March 2006

Research

Serosurvey on Household Contacts of Marburg Hemorrhagic Fever Patients

Matthias Borchert*Comments to Author , Sabue Mulangu†, Robert Swanepoel‡, Modeste Lifenya Libande§, Antoine Tshomba¶, Amayo Kulidri§, Jean-Jacques Muyembe-Tamfum†, and Patrick Van der Stuyft*
Author affiliations: *Institute of Tropical Medicine, Antwerp, Belgium; †Institut de Recherche Biomédicale, Kinshasa, Democratic Republic of Congo; ‡National Institute for Communicable Diseases, Johannesburg, South Africa; §Ministry of Health, Democratic Republic of Congo; ¶Hôpital Général de Kilo-Moto, Watsa, Democratic Republic of Congo

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Table 1

Symptoms in 121 household and community contacts within 4 weeks after exposure to a Marburg hemorrhagic fever patient, Watsa Subdistrict, Democratic Republic of Congo, 2002

Symptoms No. seronegative (%),
n = 119 No. seropositive (%),
n = 2 Total (%),
N = 121
Fever 37 (31.1) 1 38 (31.4)
General symptoms
Headache 55 (46.2) 1 56 (46.3)
Fatigue 45 (37.8) 2 47 (38.8)
Loss of appetite 39 (32.8) 1 40 (33.6)
Joint pain 33 (27.7) 1 34 (28.1)
Muscle pain 26 (21.9) 1 27 (22.3)
Back pain 24 (20.2) 1 25 (20.7)
Abdominal pain 23 (19.3) 2 25 (20.7)
Chest pain 14 (11.8) 2 16 (13.2)
Nausea, vomiting 10 (8.4) 2 12 (9.9)
Diarrhea 11 (9.2) 1 12 (9.9)
Dyspnea 8 (6.7) 2 10 (8.3)
Sore throat 8 (6.7) 1 9 (7.4)
Hiccough 3 (2.5) 2 5 (4.1)
Any general symptom 68 (57.1) 2 70 (57.9)
Hemorrhage
Nose bleed 2 (1.7) 0 2 (1.7)
Bloody/black stool 1 (0.8) 1 2 (1.7)
Coughing blood 1 (0.8) 1 2 (1.7)
Bloody vomit 0 1 1 (0.8)
Vaginal bleeding 1 (0.8) 0 1 (0.8)
Any hemorrhage 3 (2.5) 1 4 (3.3)
Combinations
Fever + >3 general symptoms 32 (26.9) 1 33 (27.3)
Fever + hemorrhage 2 (1.7) 1 3 (2.5)
Clinically suspect case* 32 (26.9) 1 33 (27.3)
Total 119 (100.0) 2 121 (100.0)

*Fever + >3 general symptoms or fever + hemorrhage.

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