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Volume 12, Number 3—March 2006

Research

West Nile Virus Infections Projected from Blood Donor Screening Data, United States, 2003

Michael P. Busch*†Comments to Author , David J. Wright‡, Brian Custer*, Leslie H. Tobler*, Susan L. Stramer§, Steven H. Kleinman*‡¶, Harry E. Prince#, Celso Bianco**, Gregory Foster§, Lyle R. Petersen††, George Nemo‡‡, and Simone A. Glynn‡
Author affiliations: *Blood Systems Research Institute, San Francisco, California, USA; †University of California, San Francisco, California, USA; ‡Westat, Rockville, Maryland, USA; §American Red Cross National Testing and Reference Laboratories, Gaithersburg, Maryland, USA; ¶University of British Columbia, Victoria, British Columbia, Canada; #Focus Diagnostics, Cypress, California, USA; **America's Blood Centers, Washington DC, USA; ††Centers for Disease Control and Prevention, Fort Collins, Colorado, USA; ‡‡National Heart, Lung, and Blood Institute, Bethesda, Maryland, USA

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Table

Estimated WNV seasonal incidence and related measures of WNV infection for each state and entire United States, 2003*

State No. MP-NAT–positive donations, 4-mo period No. donations, 4-mo period Estimated WNV seasonal incidence, % (95% CI) Midyear population estimate† Estimated no. infections Neuroinvasive cases reported to CDC‡
Alabama 3 48,044 0.12 (0.00–0.27) 4,500,752 5,336 25
Alaska 0 8,444 0.00 (0.00–0.00) 648,818 0 0
Arizona 2 86,157 0.04 (0.00–0.10) 5,580,811 2,291 7
Arkansas 1 49,750 0.04 (0.00–0.12) 2,725,714 1,050 23
California 2 394,470 0.01 (0.00–0.02) 35,484,453 3,231 2
Colorado 157 65,739 4.33 (1.83–6.83) 4,550,688 197,028 621
Connecticut 1 52,410 0.03 (0.00–0.10) 3,483,372 1,121 12
Delaware 3 19,853 0.28 (0.00–0.63) 817,491 2,268 12
District of Columbia 0 3,055 0.00 (0.00–0.00) 563,384 0 3
Florida 6 248,198 0.05 (0.00–0.09) 17,019,068 7,677 61
Georgia 6 118,981 0.09 (0.00–0.18) 8,684,715 7,803 27
Hawaii 0 16,981 0.00 (0.00–0.00) 1,257,608 0 0
Idaho 0 23,204 0.00 (0.00–0.00) 1,366,332 0 0
Illinois 15 236,926 0.11 (0.03–0.20) 12,653,544 14,399 30
Indiana 4 111,090 0.06 (0.00–0.14) 6,195,643 3,944 15
Iowa 6 89,649 0.12 (0.00–0.23) 2,944,062 3,476 81
Kansas 70 59,673 2.13 (0.85–3.42) 2,723,507 58,136 89
Kentucky 3 68,674 0.08 (0.00–0.18) 4,117,827 3,298 11
Louisiana 6 56,284 0.19 (0.00–0.38) 4,496,334 8,649 101
Maine 0 24,968 0.00 (0.00–0.00) 1,305,728 0 12
Maryland 7 75,403 0.17 (0.01–0.33) 5,508,909 9,418 49
Massachusetts 0 65,914 0.00 (0.00–0.00) 6,433,422 0 12
Michigan 7 174,776 0.07 (0.01–0.14) 10,079,985 7,122 14
Minnesota 22 114,571 0.35 (0.11–0.59) 5,059,375 17,589 48
Mississippi 6 47,980 0.23 (0.01–0.45) 2,881,281 6,548 34
Missouri 9 124,644 0.13 (0.02–0.24) 5,704,484 7,342 39
Montana 8 19,984 0.76 (0.08–1.43) 917,621 6,956 75
Nebraska 161 61,516 4.87 (2.06–7.68) 1,739,291 84,648 194
Nevada 1 32,651 0.06 (0.00–0.17) 2,241,154 1,267 2
New Hampshire 0 24,595 0.00 (0.00–0.00) 1,287,687 0 2
New Jersey 9 98,008 0.17 (0.02–0.31) 8,638,396 14,269 21
New Mexico 10 25,130 0.73 (0.12–1.34) 1,874,614 13,701 74
New York 10 245,357 0.07 (0.01–0.13) 19,190,115 13,774 57
North Carolina 1 146,807 0.01 (0.00–0.04) 8,407,248 1,087 16
North Dakota 30 13,971 4.14 (1.40–6.88) 633,837 26,264 94
Ohio 13 214,819 0.11 (0.02–0.19) 11,435,798 12,112 84
Oklahoma 23 98,287 0.43 (0.13–0.73) 3,511,532 15,196 56
Oregon 1 72,337 0.03 (0.00–0.08) 3,559,596 966 0
Pennsylvania 14 255,806 0.10 (0.02–0.17) 12,365,455 12,010 145
Rhode Island 0 580 0.00 (0.00–0.00) 1,076,164 0 5
South Carolina 0 70,369 0.00 (0.00–0.00) 4,147,152 0 3
South Dakota 46 20,430 4.02 (1.50–6.54) 764,309 30,716 151
Tennessee 4 88,532 0.08 (0.00–0.17) 5,841,748 4,797 21
Texas 80 309,469 0.48 (0.19–0.77) 22,118,509 106,013 431
Utah 0 35,448 0.00 (0.00–0.00) 2,351,467 0 0
Vermont 0 16,616 0.00 (0.00–0.00) 619,107 0 0
Virginia 1 77,634 0.02 (0.00–0.07) 7,386,330 1,623 19
Washington 0 93,469 0.00 (0.00–0.00) 6,131,445 0 0
West Virginia 1 25,560 0.07 (0.00–0.23) 1,810,354 1,342 1
Wisconsin 4 142,456 0.05 (0.00–0.11) 5,472,299 2,863 7
Wyoming 17 9,904 3.48 (0.94–6.02) 501,242 17,439 92
Total 770 4,585,573 0.25 (0.11–0.39) 290,809,777 735,000 (322,000–1,147,000)§ 2,866

*WNV, West Nile virus; MP-NAT, minipool-nucleic acid amplification testing; CI, confidence intervals.
†US Census Bureau (22).
‡Source: Centers for Disease Control and Prevention (23).
§Confidence intervals.

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