Skip directly to search Skip directly to A to Z list Skip directly to page options Skip directly to site content

Volume 12, Number 4—April 2006

Research

Atypical Enteropathogenic Escherichia coli Infection and Prolonged Diarrhea in Children

Rang N. Nguyen*1, Louise S. Taylor*†, Marija Tauschek*†, and Roy M. Robins-Browne*†Comments to Author 
Author affiliations: *University of Melbourne, Parkville, Australia; †Murdoch Children's Research Institute, Parkville, Victoria, Australia

Main Article

Table 4

Association between presumed etiologic agent and clinical and laboratory findings in children with diarrhea*

Clinical or laboratory parameter Presumed etiologic agent
EPEC,
n = 25 Adenovirus,
n = 22 Rotavirus,
n = 55 Campylobacter,
n = 30 Salmonella,
n = 22 NPI,
n = 46
Age in months, median (interquartile range) 16.9 (11.4–28.2) 9.5 (4.4–19.5)† 15.2 (9.4–28.0) 34.2 (26.9–98.1)‡§ 29.8 (9.3–90.9)¶ 11.6 (3.1–52.7)
Sex, no. (% male) 18 (72)¶ 14 (64) 30 (55) 17 (57) 10 (46) 20 (44)†
Vomiting, no. (%) 11 (44) 17 (77)†¶ 49 (89)‡§ 13 (43) 7 (32) 23 (50)
Abdominal pain, no. (%) 5 (20) 2 (9) ‡ 10 (18) 17 (57)#** 10 (45) 10 (22)**
Days with diarrhea, mean (95% CI) 12.1 (7.5–16.7)¶ 4.9 (3.6–6.2)‡ 6.0 (4.9–7.1)‡ 4.9 (3.9–5.9)‡ 6.5 (4.2–8.6)† 6.3 (3.5–9.0)†
Diarrhea >14 days, no. (%) 12 (48)¶ 1 (5)‡ 3 (5)‡¶ 1 (3)‡ 2 (9)# 9 (20)†
Temperature >38°C, no. (%) 6 (24) 2 (9) 30 (55)†¶ 7 (23) 17 (77)‡§ 13 (28)
Dehydration >5%, no. (%) 1 (4) 2 (9) 35 (64)‡§ 2 (7) 6 (27)† 6 (13)
Severity score, mean (95% CI) 9.0 (7.7–10.3) 8.6 (7.5–9.7) 13.5 (12.6–14.4)‡§ 8.4 (7.5–9.3) 11.3 (9.8–12.8)#** 8.3 (7.4–9.2)
Fecal blood
Macroscopic, no. (%) 0 0 0 4 (13) 3 (14) 1 (2)
Microscopic only, no. (%) 4 (16) 2 (9) 1 (2) 17 (57)¶§ 9 (41) 9 (20)
Fecal leukocytes, no. (%) 5 (20) 4 (18) 10 (18) 23 (77)‡§ 14 (64)¶# 10 (22)

*EPEC, Enteropathogenic Escherichia coli; NPI, no pathogen identified; CI, confidence interval.
†Significantly different from EPEC (Mann-Whitney U test, Fisher exact test, or Student t test, 2-tailed), p<0.05, >0.01.
‡Significantly different from EPEC (Mann-Whitney U test, Fisher exact test, or Student t test, 2-tailed), p<0.001.
§Significantly different from NPI (Mann-Whitney U test, Fisher exact test, or Student t test, 2-tailed), p<0.001.
¶Significantly different from NPI (Mann-Whitney U test, Fisher exact test, or Student t test, 2-tailed), p<0.05, >0.01.
#Significantly different from EPEC (Mann-Whitney U test, Fisher exact test, or Student t test, 2-tailed), p<0.01, >0.001.
**Significantly different from NPI (Mann-Whitney U test, Fisher exact test, or Student t test, 2 tailed, p<0.01, >0.001.

Main Article

1Present address: An Giang General Hospital, Long Xuyen City, An Giang, Vietnam.

TOP