Emerging Infectious Disease ISSN: 1080-6059

Isoniazid Preventive Therapy and Risk for Resistant Tuberculosis

Maria Elvira Balcells*¹, Sara L. Thomas*, Peter Godfrey-Faussett*, and Alison D. Grant*

Author affiliations: *London School of Hygiene and Tropical Medicine, London, United Kingdom

Figure 1

Relative risk (RR) for isoniazid resistance associated with isoniazid preventive therapy in 13 studies. A) Using definition (a) of resistance for the Greenland study (20). B) Using definition (b) of resistance for the Greenland study. *Excluding the 4 studies with no resistant cases in 1 or both of the 2 groups. The squares and horizontal lines represent the relative risk (RR) and 95% confidence intervals (CIs) for each study. The diamonds represent the summary RR and 95% CIs.

Figure 1. Relative risk (RR) for isoniazid resistance associated with isoniazid preventive therapy in 13 studies. A) Using definition (a) of resistance for the Greenland study (20). B) Using definition (b) of resistance for the Greenland study. *Excluding the 4 studies with no resistant cases in 1 or both of the 2 groups. The squares and horizontal lines represent the relative risk (RR) and 95% confidence intervals (CIs) for each study. The diamonds represent the summary RR and 95% CIs.

Main Article

¹Current affiliation: Department of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile

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