Rifampin-resistant Neisseria meningitidis
Figure. Blood bacterial counts in 6-week-old female BALB/c mice (Janvier, France), challenged intraperitoneally with standardized inocula of 107 colony forming units (CFU) of rifampin-susceptible (RifS) isolates and their corresponding rifampin-resistant (RifR) isolates. Bacteremia was followed at 2 and 4 h after challenge. Only results after 4 h of challenge are shown. The name of the isolates tested, their phenotype (susceptibility to rifampin, RifS or RifR, residue at the position 552 and serogroups B, C, and A), and their genotype (sequence type ST) are indicated. Results are the means ± standard error (bars) from groups of at least 5 mice (the number of mice, n, is given above each histogram). p values were determined by 2-tailed Student t test.