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Volume 12, Number 6—June 2006

Research

Norwalk Virus–specific Binding to Oyster Digestive Tissues

Françoise S. Le Guyader*Comments to Author , Fabienne Loisy*, Robert L. Atmar†, Anne M. Hutson†, Mary K. Estes†, Nathalie Ruvoën-Clouet‡§¶, Monique Pommepuy*, and Jacques Le Pendu§¶
Author affiliations: *Institut Français de Recherche pour l'Exploitation de la Mer, Nantes, France; †Baylor College of Medicine, Houston, Texas, USA; ‡Ecole Nationale Vétérinaire, Nantes, France; §Institut National de la Santé et de la Recherche Médicale, Nantes, France; ¶Université de Nantes, Nantes, France

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Table 3

Lectin binding to oyster digestive tissues and inhibitory effect on binding of Norwalk viruslike particles (VLPs)

Lectin* Binding (μg/mL)† VLP inhibition (μg/mL)‡
DBA 1 None
UEA-1 50 None
HPA 1 25

*Derived from Dolichos biflorus (DBA), Ulex europaeus (UEA-1), and Helix pomatia (HPA).
†Lowest concentration showing binding to digestive tissues.
‡Lowest dilution showing a complete inhibition of VLP binding to digestive tissues. None indicates no inhibition at 50 μg/mL.

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