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Volume 12, Number 7—July 2006

Dispatch

Smallpox during Pregnancy and Maternal Outcomes

Hiroshi Nishiura*†Comments to Author 
Author affiliation: *University of Tübingen, Tübingen, Germany; †Hiroshima University, Hiroshima, Japan

Main Article

Table 1

Case fatality among pregnant women with smallpox by gestational age, according to data from 19th- and early 20th-century outbreaks*

Reference Gestational age <3 mo
Gestational age 4–6 mo
Gestational age 7–9 mo
D/C CF (95% CI) D/C CF (95% CI) D/C CF (95% CI)
Meyer (9), 1868–1872 3/33 9.0 (0.0–18.9) 11/33 33.3 (17.2–49.4) 8/10 80.0 (55.2–100.0)
Welch (10), 1878 4/12 33.3 (6.7–60.0) 4/22 18.2 (2.1–34.3) 6/12 50.0 (21.7–78.3)
Queirel (18), 1906 2/4 50.0 (1.0–99.0) 7/10 14.5 (41.6–98.4) 1/5 17.9 (0.0–55.1)
Rao (5), 1959–1962 7/21 33.3 (13.2–53.5) 16/65 24.6 (14.1–35.1) 34/94 36.2 (26.5–45.9)
Total 16/70 22.9 (2.3–43.4) 38/130 29.2 (14.8–43.7) 49/121 40.5 (26.8–54.2)

*D/C, smallpox deaths/cases; CF, case fatality; CI, confidence interval.

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