Volume 12, Number 8—August 2006
Research
Carbapenem Resistance in Klebsiella pneumoniae Not Detected by Automated Susceptibility Testing
Fred C. Tenover*
, Rajinder K. Kalsi†, Portia P. Williams‡, Roberta B. Carey*, Sheila Stocker*, David Lonsway*, J. Kamile Rasheed*, James W. Biddle*, John E. McGowan‡, and Bruce Hanna†
, Rajinder K. Kalsi†, Portia P. Williams‡, Roberta B. Carey*, Sheila Stocker*, David Lonsway*, J. Kamile Rasheed*, James W. Biddle*, John E. McGowan‡, and Bruce Hanna†Table 2
Summary of antimicrobial susceptibility testing results for 15 test isolates*
| Method (software) | Card/panel | Imipenem results (n = 15) |
Meropenem results (n = 15) |
||||
|---|---|---|---|---|---|---|---|
| Resistant | Intermediate | Susceptible | Resistant | Intermediate | Susceptible | ||
| Broth microdilution | In-house frozen panel | 13 | 2 | 0 | 14 | 1 | 0 |
| Disk diffusion | BDDS disks | 3 | 11 | 1 | 10 | 5 | 0 |
| MicroScan (LabPro1.51, Alert 1.50) | Neg combo 32 | 7 | 7 | 1 | 13 | 1 | 1 |
| Phoenix (4.05W/3.81A) | NMIC/ ID-104 | 5 | 8 | 2 | 12 | 1 | 2 |
| Sensititre AutoReader (3.0.8 SP2) | GN2F | 0 | 2 | 13 | 0 | 3 | 12 |
| VITEK (R10.01) | Superflex GNS 122 and 127 | 5 | 0 | 10 | 2 | 3 | 10 |
| VITEK 2* (R04.01) | GN07 | 4 | 6 | 5 | 4 | 4 | 5 |
*No meropenem interpretations were given by the Advanced Expert System for 2 organisms.
