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Volume 13, Number 1—January 2007

Research

Similar Biochemical Signatures and Prion Protein Genotypes in Atypical Scrapie and Nor98 Cases, France and Norway

Jean-Noël Arsac*, Olivier Andreoletti†, Jean-Marc Bilheude‡, Caroline Lacroux†, Sylvie L. Benestad§, and Thierry G.M. Baron*Comments to Author 
Author affiliations: *Agence Française de Sécurité Sanitaire des Aliments, Lyon, France; †Ecole Nationale Vétérinaire de Toulouse, Toulouse, France; ‡Bio-Rad, Marnes-la-Coquette, France; §National Veterinary Institute, Oslo, Norway;

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Figure 2

Figure 2 - Western blot profiles of PrPres in an atypical scrapie isolate (lane 2) detected by using N-terminal (4F2, P4), central (Sha31), or C-terminal (99/97.6.1) monoclonal antibodies. Molecular weight (MW) standard (lane 1). Immunoreactivities obtained with each antibody on 10 different atypical scrapie isolates are indicated (+, strong, ±, low, –, absent).

Figure 2. Western blot profiles of PrPres in an atypical scrapie isolate (lane 2) detected by using N-terminal (4F2, P4), central (Sha31), or C-terminal (99/97.6.1) monoclonal antibodies. Molecular weight (MW) standard (lane 1). Immunoreactivities obtained with each antibody on 10 different atypical scrapie isolates are indicated (+, strong, ±, low, –, absent).

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