Blood Transfusion and Spread of Variant Creutzfeldt-Jakob Disease
Figure 2. Absolute prevalence of infection for an incubation period of 16 (A) and 50 (B) years, for nonrecipients of blood transfusion (solid, black), recipients under the assumption of no infectivity (dashed, grey), of 100% infectivity without donor exclusion (dotted, black), and 100% infectivity with donor exclusion (solid, gray). The prevalence declines after the alimentary route of transmission is interrupted, i.e., after 10 years. Prevalence differs only slightly if the infection probability of a transfusion from an infected donor is increased from 0% to 100%. Donor exclusion produces negligible reductions.