TY - JOUR AU - Cui, Jie AU - Han, Naijian AU - Streicker, Daniel AU - Li, Gang AU - Tang, Xianchun AU - Shi, Zhengli AU - Hu, Zhihong AU - Zhao, Guoping AU - Fontanet, Arnaud AU - Guan, Yi AU - Wang, Linfa AU - Jones, Gareth AU - Field, Hume E. AU - Zhang, Shuyi AU - Daszak, Peter T1 - Evolutionary Relationships between Bat Coronaviruses and Their Hosts T2 - Emerging Infectious Disease journal PY - 2007 VL - 13 IS - 10 SP - 1526 SN - 1080-6059 AB - Recent studies have suggested that bats are the natural reservoir of a range of coronaviruses (CoVs), and that rhinolophid bats harbor viruses closely related to the severe acute respiratory syndrome (SARS) CoV, which caused an outbreak of respiratory illness in humans during 2002–2003. We examined the evolutionary relationships between bat CoVs and their hosts by using sequence data of the virus RNA-dependent RNA polymerase gene and the bat cytochrome b gene. Phylogenetic analyses showed multiple incongruent associations between the phylogenies of rhinolophid bats and their CoVs, which suggested that host shifts have occurred in the recent evolutionary history of this group. These shifts may be due to either virus biologic traits or host behavioral traits. This finding has implications for the emergence of SARS and for the potential future emergence of SARS-CoVs or related viruses. KW - Phylogeny KW - coronaviruses KW - bats KW - SARS KW - phylogeography KW - evolution KW - host shifts KW - research KW - China DO - 10.3201/eid1310.070448 UR - https://wwwnc.cdc.gov/eid/article/13/10/07-0448_article ER - End of Reference