Studies of Reservoir Hosts for Marburg Virus
Figure 2. Phylogenetic analysis created by using a neighbor-joining algorithm (MEGA version 3.1, ) that related sequences of 302-nt fragments of Marburg viral protein 35 gene detected in 12 bats in Durba Mine (boldface) to sequences determined for isolates from human patients in the Durba plus previous outbreaks of the disease. Six bat-derived sequences were identical to sequences from human isolates during the outbreak; 1 corresponded to a 1975 human isolate from Zimbabwe, and the remaining 5 represented novel sequences, making a total of 15 distinct MARV sequences found to be in circulation during the Durba epidemic. Bootstrap values were determined by 500 replicates. DRC, Democratic Republic of the Congo; GER, Germany; KEN, Kenya; ZIM, Zimbabwe.