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Volume 13, Number 2—February 2007

Dispatch

Characteristics of Staphylococcus aureus Infections, Chicago Pediatric Hospital

Preeti Jaggi*, Suzanne M. Paule†, Lance R. Peterson†, and Tina Q. Tan*Comments to Author 
Author affiliations: *Northwestern University, Chicago, Illinois, USA; †Evanston Northwestern Healthcare, Evanston, Illinois, USA;

Main Article

Table 1

Comparison of clinical characteristics between pediatric patients with invasive CA-MRSA and CA-MSSA*

CharacteristicInvasive CA-MRSA, n (%)Invasive CA-MSSA, n (%)p value
Race
Black16/18 (88)3/10 (30).01
Caucasian02/10 (20).01
Hispanic1/18 (6)5/10 (50).01
Other00.01
Unknown1/18 (6)1/10 (10).01
Days of discordant therapy (CA-MRSA)
Mean ± SD (range)2.22 ± 1.76 (0–6)N/A
Days febrile, mean ± SD (range)7.0 ± 4 (0–17)5.20 ± 10.0 (0–32).03
Days in hospital, mean ± SD (range)14.2 ± 7.6 (4–28)13.8 ± 16.8 (4–60)NS
Diagnosis†
Osteomyelitis, acute3/18 (38)1/10 (10)NS
Ostyeomyelitis, chronic2/18 (11)4/10 (40)NS
Bacteremia5/18 (28)2/10 (20)NS
Endocarditis0/18 (0)2/10 (20)NS
Pyomyositis2/18 (11)0/10 (0)NS
Liver abscess1/18 (6)0/10 (0)NS
Pneumonia + empyema6/18 (33)1/10 (10)NS
Septic joint1/18 (6)2/10 (20)NS
Fasciitis1/18 (6)0/10 (0)NS
Toxic-shock syndrome1/18 (6)0/10 (0)NS
Other‡3/18 (38)0/10 (0)NS
Patients with >1 disease manifestation (%)7/18 (39)1/10 (10)NS
Days of illness before hospitalization, mean ± SD (range)6.9 ± 11.8 (1–45)10.9 d ± 15 (2–45)NS
Days of positive cultures, mean ± SD (range)6.94 ± 9.9 (1–45)4.4 ± 2.98 (1–11)NS
Initial leukocyte count‡ (thousand/μL), mean ± SD (range)14.8 ± 13.07 (2.4–57.0)9.95 ± 4.45 (3.3–17.0)NS

*CA-MRSA, community-associated methicillin-resistant Staphylococcus aureus; MSSA, methicillin-sensitive S. aureus; NS, not significant; SD, standard deviation. Among patients with invasive CA-MRSA infection, 1 died.
†Bonferroni correction for multiple comparisons was applied for comparisons of diagnosis.
‡Other diseases included extensive perineal abscess with fistula, subgaleal hematoma, and a subscapular abscess and prostatitis in the same patient. §One initial leukocyte count was unavailable in each patient group.

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