Skip directly to search Skip directly to A to Z list Skip directly to page options Skip directly to site content

Volume 13, Number 5—May 2007

Research

Pet Rodents and Fatal Lymphocytic Choriomeningitis in Transplant Patients

Brian R. Amman*1Comments to Author , Boris I. Pavlin*12, Cesar G. Albariño*, James A. Comer*, Bobbie R. Erickson*, Jennifer B. Oliver*, Tara K. Sealy*, Martin J. Vincent*, Stuart T. Nichol*, Christopher D. Paddock*, Abbigail J. Tumpey*, Kent D. Wagoner*3, R. David Glauer†, Kathleen A. Smith‡, Kim A. Winpisinger‡, Melody S. Parsely§, Phil Wyrick¶, Christopher H. Hannafin#, Utpala Bandy**, Sherif R. Zaki*, Pierre E. Rollin*, and Thomas G. Ksiazek*

Author affiliations: *Centers for Disease Control and Prevention, Atlanta, Georgia, USA; †Ohio Department of Agriculture, Reynoldsburg, Ohio, USA; ‡Ohio Department of Health, Columbus, Ohio, USA; §Arkansas Department of Health and Human Services, Little Rock, Arkansas, USA; ¶Arkansas Department of Agriculture, Little Rock, Arkansas, USA; #Rhode Island Department of Environmental Management, Providence, Rhode Island, USA; **Rhode Island Department of Public Health, Providence, Rhode Island, USA;

Main Article

Table 2

Results of laboratory testing on the index hamster and traceback rodents associated with organ transplantation transmission of LCMV*

Rodent† IFA ELISA IHC RT-PCR/ TaqMan Virus
isolation Sequence
(L gene)
Index hamster
ND
Neg
Pos
Pos
Pos
232 bp
Pet store hamster 1
Pos
Neg
Pos
Pos
Pos
232 bp
Pet store hamster 2
Neg
Neg
Pos
Pos
Pos
232 bp
Pet store guinea pig 1
ND
Neg
Pos
Pos
Pos
232 bp
Ohio hamster 1
Pos
Neg
Pos
Pos
Pos
232 bp
Ohio Hamster 2
Pos
Neg
Pos
Pos
Pos
NA
Ohio hamster 3
Pos
Neg
ND
Neg
Neg
NA
Ohio hamster 4
Neg
Neg
Pos
Pos
Pos
NA
Ohio hamster 5 Neg Neg Neg ND Pos NA

*LCMV, lymphocytic choriomeningitis virus; IFA, immunofluorescent antibody assay; IHC, immunohistochemistry; RT-PCR, reverse transcription–PCR; ND, no data; Neg, negative; Pos, positive; NA, no amplification (could not get traditional PCR primers to amplify, for sequencing).
†The table includes only those rodents that tested positive with ≥1 test.

Main Article

1These authors contributed equally to this article.

2Current affiliation: Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA

3Current affiliation: Ithaca College, Ithaca, New York, USA

TOP