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Volume 13, Number 6—June 2007

Research

Isolation and Characterization of Novel Human Parechovirus from Clinical Samples

Kanako Watanabe*†, Masayasu Oie*, Masaya Higuchi*, Makoto Nishikawa†, and Masahiro Fujii*Comments to Author 
Author affiliations: *Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan; †Niigata Prefectural Institute of Public Health and Environmental Sciences, Niigata, Japan

Main Article

Table 2

Comparisons of nucleotide and amino acid sequences among NII561-2000, HPeV-1, HPeV-2, HPeV-3, HPeV-4, and HPeV-5*

Sequence % Nucleotide similarity (% amino acid similarity) with NII561-2000
HPeV-1† HPeV-2 HPeV-3 HPeV-4 HPeV-5
5′UTR 85.3 87.3 86.9 88.5 86.9
VP0 73.6 (78.2) 76.0 (80.9) 70.6 (72.3) 72.6 (81.0) 73.1 (77.2)
VP3 74.4 (84.7) 73.0 (80.2) 67.0 (74.1) 70.9 (78.0) 68.7 (73.1)
VP1 71.7n(80.3) 67.3 (72.2) 71.1 (75.3) 70.0 (71.9) 66.2 (70.2)
2A 80.8 (90.7) 77.1 (88.0) 81.0 (85.3) 77.3 (91.2) 76.2 (88.7)
2B 78.6 (97.5) 77.8 (97.5) 82.0 (97.5) 79.8 (97.5) 78.7 (99.2)
2C 84.7 (97.3) 76.4 (86.9) 79.2 (92.7) 78.7 (92.4) 79.2 (93.6)
3A 85.7 (96.6) 77.4 (88.0) 78.0 (87.2) 75.5 (89.7) 78.6 (83.8)
3B 81.4 (80.0) 72.9 (80.0) 73.3 (75.0) 66.7 (85.0) 70.0 (85.0)
3C 84.2 (99.0) 82.7 (99.0) 82.3 (98.0) 82.5 (98.0) 80.5 (99.0)
3D 83.2 (95.9) 83.7 (95.5) 83.9 (95.7) 84.2 (96.8) 87.2 (97.0)
3′UTR 81.6 88.5 83.9 84.9 93.2
ORF 79.5 (90.7) 77.1 (87.3) 76.7 (85.9) 77.1 (88.2) 77.0 (86.9)

*HPeV, human parechovirus; UTR, untranslated region; ORF, open reading frame.
†The HPeV strains used were Harris strain for HPeV-1, Williamson strain for HPeV-2, A308/99 for HPeV-3, K2511876–02 for HPeV-4, and CT86–6760 for HPeV-5.

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